Fingerprinting and profiling in metabolomics of biosamples

V Ghini, G Meoni, A Vignoli, F Di Cesare… - Progress in Nuclear …, 2023 - Elsevier
This review focuses on metabolomics from an NMR point of view. It attempts to cover the
broad scope of metabolomics and describes the NMR experiments that are most suitable for …

Rapid and Self-Administrable Capillary Blood Microsampling Demonstrates Statistical Equivalence with Standard Venous Collections in NMR-Based Lipoprotein …

JL Roberts, L Whiley, N Gray, M Gay… - Analytical …, 2024 - ACS Publications
We investigated plasma and serum blood derivatives from capillary blood microsamples
(500 μL, MiniCollect tubes) and corresponding venous blood (10 mL vacutainers). Samples …

[HTML][HTML] Metabolomic profiling of CSF and blood serum elucidates general and sex-specific patterns for mild cognitive impairment and Alzheimer's disease patients

G Berezhnoy, C Laske, C Trautwein - Frontiers in aging …, 2023 - ncbi.nlm.nih.gov
Background Beta-amyloid (Abeta) and tau protein in cerebrospinal fluid (CSF) are
established diagnostic biomarkers for Alzheimer's disease (AD). However, these biomarkers …

[HTML][HTML] COVID-19 and Comorbidities: What Has Been Unveiled by Metabolomics?

ALM Camelo, HR Zamora Obando, I Rocha, AC Dias… - Metabolites, 2024 - mdpi.com
The COVID-19 pandemic has brought about diverse impacts on the global population.
Individuals with comorbidities were more susceptible to the severe symptoms caused by the …

[HTML][HTML] Maintained imbalance of triglycerides, apolipoproteins, energy metabolites and cytokines in long-term COVID-19 syndrome patients

G Berezhnoy, R Bissinger, A Liu, C Cannet… - Frontiers in …, 2023 - frontiersin.org
Background Deep metabolomic, proteomic and immunologic phenotyping of patients
suffering from an infection with severe acute respiratory syndrome coronavirus 2 (SARS …

[HTML][HTML] Urinary phenotyping of SARS-CoV-2 infection connects clinical diagnostics with metabolomics and uncovers impaired NAD+ pathway and SIRT1 activation

C Lonati, G Berezhnoy, N Lawler, R Masuda… - Clinical Chemistry and …, 2024 - degruyter.com
Objectives The stratification of individuals suffering from acute and post-acute SARS-CoV-2
infection remains a critical challenge. Notably, biomarkers able to specifically monitor viral …

[HTML][HTML] Integrated NMR and MS Analysis of the Plasma Metabolome Reveals Major Changes in One-Carbon, Lipid, and Amino Acid Metabolism in Severe and Fatal …

MC Gama-Almeida, GDA Pinto, L Teixeira, ED Hottz… - Metabolites, 2023 - mdpi.com
Brazil has the second-highest COVID-19 death rate worldwide, and Rio de Janeiro is among
the states with the highest rate in the country. Although vaccine coverage has been …

[HTML][HTML] HDL-related parameters and COVID-19 mortality: the importance of HDL function

JT Stadler, H Habisch, F Prüller, H Mangge… - Antioxidants, 2023 - mdpi.com
COVID-19, caused by the SARS-CoV-2 coronavirus, emerged as a global pandemic in late
2019, resulting in significant global public health challenges. The emerging evidence …

[HTML][HTML] Longitudinal NMR-Based Metabolomics Study Reveals How Hospitalized COVID-19 Patients Recover: Evidence of Dyslipidemia and Energy Metabolism …

L Ansone, V Rovite, M Brīvība, L Jagare… - International Journal of …, 2024 - mdpi.com
Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), can manifest as long-
term symptoms in multiple organ systems, including respiratory, cardiovascular …

[HTML][HTML] Cathepsin S Is More Abundant in Serum of Mycobacterium avium subsp. paratuberculosis-Infected Dairy Cows

HC Duda, C von Toerne, L Korbonits, A Didier… - Metabolites, 2024 - mdpi.com
Mycobacterium avium subsp. paratuberculosis (MAP) is the causative agent of bovine
paratuberculosis, a chronic granulomatous enteritis leading to economic losses and posing …