COVID-19 and cellular senescence

CA Schmitt, T Tchkonia, LJ Niedernhofer… - Nature Reviews …, 2023 - nature.com
The clinical severity of coronavirus disease 2019 (COVID-19) is largely determined by host
factors. Recent advances point to cellular senescence, an ageing-related switch in cellular …

COVID-19 and preexisting comorbidities: risks, synergies, and clinical outcomes

B Bigdelou, MR Sepand, S Najafikhoshnoo… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated
symptoms, named coronavirus disease 2019 (COVID-19), have rapidly spread worldwide …

Traditional Chinese Medicine (TCM) in the treatment of COVID-19 and other viral infections: Efficacies and mechanisms

K Huang, P Zhang, Z Zhang, JY Youn, C Wang… - Pharmacology & …, 2021 - Elsevier
COVID-19 has remained an uncontained, worldwide pandemic. While battling for the
disease in China, six Traditional Chinese Medicine (TCM) recipes have been shown to be …

The miRNA: a small but powerful RNA for COVID-19

S Zhang, K Amahong, X Sun, X Lian, J Liu… - Briefings in …, 2021 - academic.oup.com
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is a severe and rapidly evolving epidemic. Now …

Association of COVID-19 with comorbidities: An update

S Chatterjee, LV Nalla, M Sharma… - ACS Pharmacology & …, 2023 - ACS Publications
Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome-
coronavirus-2 (SARS-CoV-2) which was identified in Wuhan, China in December 2019 and …

[HTML][HTML] Manganese molybdate nanodots with dual amplification of STING activation for “cycle” treatment of metalloimmunotherapy

H Lei, Q Li, G Li, T Wang, X Lv, Z Pei, X Gao, N Yang… - Bioactive Materials, 2024 - Elsevier
Certain types of cationic metal ions, such as Mn 2+ are able to activate immune functions via
the stimulator of interferon genes (STING) pathway, showing potential applications in …

Endothelial cell dysfunction, coagulation, and angiogenesis in coronavirus disease 2019 (COVID-19)

AH Norooznezhad, K Mansouri - Microvascular research, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has been led to a pandemic emergency. So far …

The intersection of COVID-19 and cancer: signaling pathways and treatment implications

Z Zong, Y Wei, J Ren, L Zhang, F Zhou - Molecular cancer, 2021 - Springer
The outbreak of the novel coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged as a serious public health …

Adipocytes encapsulating telratolimod recruit and polarize tumor‐associated macrophages for cancer immunotherapy

D Wen, T Liang, G Chen, H Li, Z Wang… - Advanced …, 2023 - Wiley Online Library
Tumor‐associated adipocytes (TAAs) recruit monocytes and promote their differentiation into
tumor‐associated macrophages (TAMs) that support tumor development. Here, TAAs are …

Dual action anti‐inflammatory/antiviral isoquinoline alkaloids as potent naturally occurring anti‐SARS‐CoV‐2 agents: A combined pharmacological and medicinal …

M Valipour, A Hosseini, A Di Sotto… - Phytotherapy …, 2023 - Wiley Online Library
In the search for compounds that inhibit the SARS‐CoV‐2 after the onset of the COVID‐19
pandemic, isoquinoline‐containing alkaloids have been identified as compounds with high …