Oxidative stress in human pathology and aging: molecular mechanisms and perspectives

YA Hajam, R Rani, SY Ganie, TA Sheikh, D Javaid… - Cells, 2022 - mdpi.com
Reactive oxygen and nitrogen species (RONS) are generated through various endogenous
and exogenous processes; however, they are neutralized by enzymatic and non-enzymatic …

A review on acrylamide in food: Occurrence, toxicity, and mitigation strategies

L Rifai, FA Saleh - International journal of toxicology, 2020 - journals.sagepub.com
Acrylamide (AA) is a food contaminant present in a wide range of frequently consumed
foods, which makes human exposure to this toxicant unfortunately unavoidable. However …

Protective effects of morin against acrylamide-induced hepatotoxicity and nephrotoxicity: A multi-biomarker approach

FM Kandemir, S Yıldırım, S Kucukler… - Food and chemical …, 2020 - Elsevier
Acrylamide (ACR) is a heat-induced carcinogen substance that is found in some foods due
to cooking or other thermal processes. The aim of present study was to assess the probable …

Evaluation of therapeutic effects of quercetin against Achilles tendinopathy in rats via oxidative stress, inflammation, apoptosis, autophagy, and metalloproteinases

HS Semis, C Gur, M Ileriturk… - … American journal of …, 2022 - journals.sagepub.com
Background: Achilles tendinopathy, seen in athletes and manual labor workers, is an
inflammatory condition characterized by chronic tendon pain. Owing to the toxicity that …

Morin protects against acrylamide-induced neurotoxicity in rats: an investigation into different signal pathways

C Gur, FM Kandemir, E Darendelioglu… - … Science and Pollution …, 2021 - Springer
The presented study investigates the effects of morin against toxicity induced by acrylamide
(ACR) in the brains of Sprague Dawley rats. In this study, neurotoxicity was induced by orally …

Protective effect of quercetin on kidney diseases: From chemistry to herbal medicines

YQ Chen, HY Chen, QQ Tang, YF Li, XS Liu… - Frontiers in …, 2022 - frontiersin.org
Kidney injuries may trigger renal fibrosis and lead to chronic kidney disease (CKD), but
effective therapeutic strategies are still limited. Quercetin is a natural flavonoid widely …

Morin attenuates acrylamide-induced testicular toxicity in rats by regulating the NF-κB, Bax/Bcl-2 and PI3K/Akt/mTOR signaling pathways

S Kucukler, C Caglayan, E Darendelioğlu… - Life Sciences, 2020 - Elsevier
Aim Acrylamide (AC) is a carcinogenic substance which is formed during the heating of
starchy foods at high temperatures and constitutes an important risk for human health …

The ameliorative effects of boron against acrylamide-induced oxidative stress, inflammatory response, and metabolic changes in rats

U Acaroz, S Ince, D Arslan-Acaroz, Z Gurler… - Food and chemical …, 2018 - Elsevier
Acrylamide (ACR) is a hazardous substance associated with the accumulation of excessive
reactive oxygen species and causes oxidative stress. Presence of ACR in foods leads to …

Neuropharmacological interventions of quercetin and its derivatives in neurological and psychological disorders

K Agrawal, P Chakraborty, S Dewanjee, S Arfin… - Neuroscience & …, 2023 - Elsevier
Quercetin is a naturally occurring bioactive flavonoid abundant in many plants and fruits.
Quercetin and its derivatives have shown an array of pharmacological activities in preclinical …

Protective effects of hesperidin and diosmin against acrylamide-induced liver, kidney, and brain oxidative damage in rats

AE Elhelaly, G AlBasher, S Alfarraj, R Almeer… - … Science and Pollution …, 2019 - Springer
Acrylamide (AA) is a heat-induced toxin formed during thermal processing of many
commonly consumed foods, including meat products, French fries, potato crisps, bread …