[HTML][HTML] Fundamental biological features of spaceflight: advancing the field to enable deep-space exploration

E Afshinnekoo, RT Scott, MJ MacKay, E Pariset… - Cell, 2020 - cell.com
Research on astronaut health and model organisms have revealed six features of
spaceflight biology that guide our current understanding of fundamental molecular changes …

[HTML][HTML] Toward sustainable space exploration: a roadmap for harnessing the power of microorganisms

R Santomartino, NJH Averesch, M Bhuiyan… - Nature …, 2023 - nature.com
Finding sustainable approaches to achieve independence from terrestrial resources is of
pivotal importance for the future of space exploration. This is relevant not only to establish …

[HTML][HTML] Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight

J Park, EG Overbey, SA Narayanan, JK Kim… - Nature …, 2024 - nature.com
Spaceflight can change metabolic, immunological, and biological homeostasis and cause
skin rashes and irritation, yet the molecular basis remains unclear. To investigate the impact …

[HTML][HTML] Horizon scanning the application of probiotics for wildlife

N Garcias-Bonet, A Roik, B Tierney, FC García… - Trends in …, 2023 - cell.com
The provision of probiotics benefits the health of a wide range of organisms, from humans to
animals and plants. Probiotics can enhance stress resilience of endangered organisms …

[HTML][HTML] Cyanobacteria and microalgae in supporting human habitation on Mars

LJ Mapstone, MN Leite, S Purton, IA Crawford… - Biotechnology …, 2022 - Elsevier
Establishing the first human presence on Mars will be the most technically challenging
undertaking yet in the exploration beyond our planet. The remoteness of Mars from Earth …

Biomonitoring and precision health in deep space supported by artificial intelligence

RT Scott, LM Sanders, EL Antonsen… - Nature Machine …, 2023 - nature.com
Human exploration of deep space will involve missions of substantial distance and duration.
To effectively mitigate health hazards, paradigm shifts in astronaut health systems are …

The Space Omics and Medical Atlas (SOMA) and international astronaut biobank

EG Overbey, JK Kim, BT Tierney, J Park, N Houerbi… - Nature, 2024 - nature.com
Spaceflight induces molecular, cellular, and physiological shifts in astronauts and poses
myriad biomedical challenges to the human body, which are becoming increasingly relevant …

Biological research and self-driving labs in deep space supported by artificial intelligence

LM Sanders, RT Scott, JH Yang, AA Qutub… - Nature Machine …, 2023 - nature.com
Abstract Space biology research aims to understand fundamental spaceflight effects on
organisms, develop foundational knowledge to support deep space exploration and …

[HTML][HTML] Towards a biomanufactory on Mars

AJ Berliner, JM Hilzinger, AJ Abel… - Frontiers in Astronomy …, 2021 - frontiersin.org
A crewed mission to and from Mars may include an exciting array of enabling
biotechnologies that leverage inherent mass, power, and volume advantages over …

[HTML][HTML] Harnessing bioengineered microbes as a versatile platform for space nutrition

B Llorente, TC Williams, HD Goold, IS Pretorius… - Nature …, 2022 - nature.com
Human enterprises through the solar system will entail long-duration voyages and habitation
creating challenges in maintaining healthy diets. We discuss consolidating multiple sensory …