RNA viruses include many important human and animal pathogens, such as the influenza
viruses, respiratory syncytial virus, Ebola virus, measles virus and rabies virus. The …

Bunyaviruses are negative sense, single-strand RNA viruses that infect a wide range of
vertebrate, invertebrate and plant hosts. WHO lists three bunyavirus diseases as priority …

Influenza polymerase (FluPol) transcribes viral mRNA at the beginning of the viral life cycle
and initiates genome replication after viral protein synthesis. However, it remains poorly …

The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
developed into an unprecedented global pandemic. Nucleoside analogs, such as …

Non-segmented negative-strand RNA viruses, including Ebola virus (EBOV), rabies virus,
human respiratory syncytial virus and pneumoviruses, can cause respiratory infections …

Abstract Tilapia Lake Virus (TiLV), a recently discovered pathogen of tilapia fish, belongs to
the Amnoonviridae family from the Articulavirales order. Its ten genome segments have …

Severe fever with thrombocytopenia syndrome virus (SFTSV) is a phenuivirus that has
rapidly become endemic in several East Asian countries. The large (L) protein of SFTSV …

Segmented negative-strand RNA bunyaviruses encode a multi-functional polymerase that
performs genome replication and transcription. Here, we establish conditions for in vitro …

Severe Fever with Thrombocytopenia Syndrome (SFTS), caused by Dabie bandavirus
(SFTSV), is an emerging infectious disease first identified in China. Since its discovery …

Hantaviruses infect a wide range of hosts including insectivores and rodents and can also
cause zoonotic infections in humans, which can lead to severe disease with possible fatal …