Stewart-Treves syndrome: pathogenesis and management

A Sharma, RA Schwartz - Journal of the American Academy of Dermatology, 2012 - Elsevier
Stewart-Treves syndrome is a malignancy that arises within chronic lymphedema. Although
classically described as a consequence of radical mastectomy, this lymphangiosarcoma has …

The lymphatic vascular system: much more than just a sewer

J Wilting, J Becker - Cell & Bioscience, 2022 - Springer
Almost 400 years after the (re) discovery of the lymphatic vascular system (LVS) by Gaspare
Aselli (Asellius G. De lactibus, sive lacteis venis, quarto vasorum mesaraicorum genere …

Consistent MYC and FLT4 gene amplification in radiation‐induced angiosarcoma but not in other radiation‐associated atypical vascular lesions

T Guo, L Zhang, NE Chang, S Singer… - Genes …, 2011 - Wiley Online Library
Angiosarcoma (AS) is a distinct group of sarcomas characterized by upregulation of vascular‐
specific receptor tyrosine kinases, including TIE1, KDR, TEK, and FLT1. In keeping with the …

Cutaneous angiosarcomas: molecular pathogenesis guides novel therapeutic approaches

LV Goerdt, SW Schneider… - JDDG: Journal der …, 2022 - Wiley Online Library
Cutaneous angiosarcoma (CAS) is a highly aggressive cancer with a poor prognosis.
Primary, spontaneous CAS (pCAS) and secondary, post‐irradiation‐or lymphedema …

Lymph vessels: the forgotten second circulation in health and disease

LA Adamczyk, K Gordon, I Kholová, LB Meijer-Jorna… - Virchows Archiv, 2016 - Springer
The lymphatic circulation is still a somewhat forgotten part of the circulatory system. Despite
this, novel insights in lymph angiogenesis in health and disease, application of immune …

Constitutive activation of mTORC1 in endothelial cells leads to the development and progression of lymphangiosarcoma through VEGF autocrine signaling

S Sun, S Chen, F Liu, H Wu, J McHugh, IL Bergin… - Cancer cell, 2015 - cell.com
Angiosarcoma/lymphangiosarcoma is a rare malignancy with poor prognosis. We generated
a mouse model with inducible endothelial-cell-specific deletion of Tsc1 to examine mTORC1 …

[HTML][HTML] Primary vascular tumors of bone: a spectrum of entities?

SLJ Verbeke, JVMG Bovée - International journal of clinical and …, 2011 - ncbi.nlm.nih.gov
Vascular tumors of bone are a heterogeneous group. Numerous terms have been
introduced as well as different classification systems. None of the classification schemes …

The utility of MYC and FLT4 in the diagnosis and treatment of postradiation atypical vascular lesion and angiosarcoma of the breast

KM Cornejo, A Deng, H Wu, EF Cosar, A Khan, MS Cyr… - Human pathology, 2015 - Elsevier
Atypical vascular lesions (AVLs) and angiosarcomas (ASs) are well-recognized
complications of radiotherapy for breast cancer. Early diagnosis may be challenging …

Breakages at YWHAE, FAM22A, and FAM22B loci in uterine angiosarcoma: a case report with immunohistochemical and genetic analysis

S Suzuki, F Tanioka, H Minato, A Ayhan… - … -Research and Practice, 2014 - Elsevier
Described herein is the first reported case of a uterine angiosarcoma with breakages at
three loci, YWHAE (17p13), FAM22A (10q23) and FAM22B (10q22). A 62-year-old …

Distinct histological features characterize primary angiosarcoma of bone

SLJ Verbeke, F Bertoni, P Bacchini, R Sciot… - …, 2011 - Wiley Online Library
Verbeke SLJ, Bertoni F, Bacchini P, Sciot R, Fletcher CDM, Kroon HM, Hogendoorn PCW &
Bovée JVMG (2011) Histopathology 58, 254–264 Distinct histological features characterize …