An immunosuppressive state is a typical feature of the tumor microenvironment. Despite the
dramatic success of immune checkpoint inhibitor (ICI) therapy in preventing tumor cell …

Epitranscriptomic modifications have recently emerged into the spotlight of researchers due
to their vast regulatory effects on gene expression and thereby cellular physiology and …

With recent progress in mapping N7-methylguanosine (m7G) RNA methylation sites, tens of
thousands of experimentally validated m7G sites have been discovered in various species …

Objective LRPPRC is a newly discovered N6-methyladenosine (m6A) modification reader,
which potentially affects hepatocellular carcinoma (HCC) progression. PD-L1 in tumor cells …

Abstract N6-methyladenosine (m6A) RNA methylation is the predominant epigenetic
modification for mRNAs that regulates various cancer-related pathways. However, the …

In addition to the four canonical nucleobases, RNA molecules undergo various chemical
modifications. To date, more than 170 structurally diverse RNA modifications have been …

Immune microenvironment could affect the biological progress in prostate cancer (PCa)
through N6 methyl adenosine (m6A) methylation. The purpose of this study was to …

Background Identifying predictive markers for breast cancer (BC) prognosis and
immunotherapeutic responses remains challenging. Recent findings indicate that N7 …

There is a pressing need for innovative therapeutic strategies for patients with epithelial
ovarian cancer (EOC). Previous studies have shown that UNC-51-like kinase 1 (ULK1), a …

Abstract The 2023 Nucleic Acids Research Database Issue contains 178 papers ranging
across biology and related fields. There are 90 papers reporting on new databases and 82 …