The current influenza vaccines are unable to provide effective protection in many cases, like
influenza viruses strain antigenic drift or shift, and the influenza continues to cause …

H7 avian influenza virus has caused multiple human infections and poses a severe public
health threat. In response to the highly variable nature of AIVs, a novel, easily regenerated …

Adjuvants are effective tools to enhance vaccine efficacy and control the type of immune
responses such as antibody and T helper 1 (Th1)-or Th2-type responses. Several studies …

Self-amplifying replicon RNA (RepRNA) promotes expansion of mRNA templates encoding
genes of interest through their replicative nature, thus providing increased antigen payloads …

According to data from the World Health Organization (WHO) every year, millions of people
are affected by flu. Flu is a disease caused by influenza viruses. For preventing this …

Most seasonal influenza vaccines are produced using hemagglutinin (HA) surface antigens
from inactivated virions. However, virions are thought to be a suboptimal source for the less …

Every year, influenza virus infections cause significant morbidity and mortality worldwide.
They pose a substantial burden of disease, in terms of not only health but also the economy …

Broadly neutralizing antibodies (bnAbs) targeting the hemagglutinin (HA) stem of influenza
A viruses (IAVs) tend to be effective against either group 1 or group 2 viral diversity. In rarer …

The COVID-19 pandemic has led to a renewed recognition of the importance of disease
prevention and public health globally. The progress in COVID-19 vaccine technology is a …

流感病毒有着极强的变异性和传播性, 常在全球范围内引起季节性的流感爆发.
流感病毒的基因组序列, 蛋白结构与功能, 病毒的包装机制等环节研究相对清楚 …