The immunology of long COVID

DM Altmann, EM Whettlock, S Liu… - Nature Reviews …, 2023 - nature.com
Long COVID is the patient-coined term for the disease entity whereby persistent symptoms
ensue in a significant proportion of those who have had COVID-19, whether asymptomatic …

[PDF][PDF] The neurobiology of long COVID

M Monje, A Iwasaki - Neuron, 2022 - cell.com
Persistent neurological and neuropsychiatric symptoms affect a substantial fraction of
people after COVID-19 and represent a major component of the post-acute COVID-19 …

[HTML][HTML] Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization

M Taquet, Z Skorniewska, A Hampshire… - Nature medicine, 2023 - nature.com
Post-COVID cognitive deficits, including 'brain fog', are clinically complex, with both objective
and subjective components. They are common and debilitating, and can affect the ability to …

[HTML][HTML] Biomarkers in long COVID-19: A systematic review

YJ Lai, SH Liu, S Manachevakul, TA Lee… - Frontiers in …, 2023 - frontiersin.org
Purpose Long COVID, also known as post-acute sequelae of COVID-19, refers to the
constellation of long-term symptoms experienced by people suffering persistent symptoms …

[HTML][HTML] Respiratory sequelae of COVID-19: pulmonary and extrapulmonary origins, and approaches to clinical care and rehabilitation

SJ Singh, MM Baldwin, E Daynes, RA Evans… - The Lancet …, 2023 - thelancet.com
Although the exact prevalence of post-COVID-19 condition (also known as long COVID) is
unknown, more than a third of patients with COVID-19 develop symptoms that persist for …

Platelets and SARS-CoV-2 during COVID-19: immunity, thrombosis, and beyond

A Sciaudone, H Corkrey, F Humphries… - Circulation …, 2023 - Am Heart Assoc
COVID-19 is characterized by dysregulated thrombosis and coagulation that can increase
mortality in patients. Platelets are fast responders to pathogen presence, alerting the …

Thrombo-inflammation in long COVID–the elusive key to post-infection sequelae?

L Nicolai, R Kaiser, K Stark - Journal of Thrombosis and Haemostasis, 2023 - Elsevier
Long COVID is a public health emergency affecting millions of people worldwide,
characterized by heterogenous symptoms across multiple organs systems. Here, we discuss …

[HTML][HTML] NETosis induction reflects COVID-19 severity and long COVID: insights from a 2-center patient cohort study in Israel

N Krinsky, S Sizikov, S Nissim, A Dror, A Sas… - Journal of Thrombosis …, 2023 - Elsevier
Background COVID-19 severity and its late complications continue to be poorly understood.
Neutrophil extracellular traps (NETs) form in acute COVID-19, likely contributing to morbidity …

Cell-specific mechanisms in the heart of COVID-19 patients

EJ Tsai, D Čiháková, NR Tucker - Circulation research, 2023 - Am Heart Assoc
From the onset of the pandemic, evidence of cardiac involvement in acute COVID-19
abounded. Cardiac presentations ranged from arrhythmias to ischemia, myopericarditis …

Randomized trial of anticoagulation strategies for noncritically ill patients hospitalized with COVID-19

GW Stone, ME Farkouh, A Lala, E Tinuoye… - Journal of the American …, 2023 - jacc.org
Background Prior studies of therapeutic-dose anticoagulation in patients with COVID-19
have reported conflicting results. Objectives We sought to determine the safety and …