Cellular senescence represents a distinct cell fate characterized by replicative arrest in
response to a host of extrinsic and intrinsic stresses. Senescence facilitates programming …

Cellular senescence, first described in vitro in 1961, has become a focus for biotech
companies that target it to ameliorate a variety of human conditions. Eminently characterized …

Cellular senescence is a stress response that elicits a permanent cell cycle arrest and
triggers profound phenotypic changes such as the production of a bioactive secretome …

Emerging autologous cellular therapies that utilize platelet-rich plasma (PRP) applications
have the potential to play adjunctive roles in a variety of regenerative medicine treatment …

Cellular senescence is a physiological mechanism whereby a proliferating cell undergoes a
stable cell cycle arrest upon damage or stress and elicits a secretory phenotype. This highly …

Senescent cells are highly associated with aging and pathological conditions and could be
targeted to slow the aging process. One commonly used marker to examine senescent cells …

The global population of individuals over the age of 65 is growing at an unprecedented rate
and is expected to reach 1.6 billion by 2050. Most older individuals are affected by multiple …

The skin, being the barrier organ of the body, is constitutively exposed to various stimuli
impacting its morphology and function. Senescent cells have been found to accumulate with …

Aging is a multifaceted and complicated process, manifested by a decline of normal
physiological functions across tissues and organs, leading to overt frailty, mortality, and …

Aging is a major cause of many degenerative diseases. The most intuitive consequence of
aging is mainly manifested on the skin, resulting in cumulative changes in skin structure …