Stem cells in kidney ischemia: from inflammation and fibrosis to renal tissue regeneration

R Cianci, M Simeoni, E Cianci, O De Marco… - International Journal of …, 2023 - mdpi.com
Ischemic nephropathy consists of progressive renal function loss due to renal hypoxia,
inflammation, microvascular rarefaction, and fibrosis. We provide a literature review focused …

Kidney organoids: steps towards better organization and function

JA Davies, I Holland, H Gül - Biochemical Society Transactions, 2024 - portlandpress.com
Kidney organoids—3D representations of kidneys made either from pluripotent or tissue
stem cells—have been available for well over a decade. Their application could confer …

Insights into repeated renal injury using RNA-Seq with two new RPTEC cell lines

BA Merrick, NP Martin, AM Brooks, JF Foley… - International Journal of …, 2023 - mdpi.com
Renal proximal tubule epithelial cells (RPTECs) are a primary site for kidney injury. We
created two RPTEC lines from CD-1 mice immortalized with hTERT (human telomerase …

An overview of the production of tissue extracellular matrix and decellularization process

S Dehghani, Z Aghaee, S Soleymani, M Tafazoli… - Cell and Tissue …, 2024 - Springer
Thousands of patients need an organ transplant yearly, while only a tiny percentage have
this chance to receive a tissue/organ transplant. Nowadays, decellularized animal tissue is …

Future therapy for end-stage renal failure: gene-edited pig kidney xenotransplantation

L Wang, Q Wei, DKC Cooper - European Journal of …, 2023 - eujtransplantation.com
In suitable patients with end-stage renal disease, the transplantation of kidneys from living or
deceased human donors offers a much-improved quality and length of life. However, the …

[引用][C] Engineering the (vascularized) Proximal Tubule, a Guide Towards Functionality

AM van Genderen - 2023 - Utrecht University