The role of the prefrontal cortex (PFC) takes center stage among unanswered questions in
modern neuroscience. The PFC has a Janus-faced nature: it enables sophisticated cognitive …

Exposure to stress during critical periods in development can have severe long-term
consequences, increasing overall risk on psychopathology. One of the key stress response …

Human pluripotent stem cells have emerged as a promising in vitro model system for
studying the brain. Two-dimensional and three-dimensional cell culture paradigms have …

The recent shift in sociopolitical debates and growing liberalization of cannabis use across
the globe has raised concern regarding its impact on vulnerable populations, such as …

The medial prefrontal cortex (mPFC) and its abundant connections with other brain regions
play key roles in memory, cognition, decision making, social behaviors, and mood …

Infectious or noninfectious maternal immune activation (MIA) is an environmental risk factor
for psychiatric and neurological disorders with neurodevelopmental etiologies. Whilst there …

Fear can be highly adaptive in promoting survival, yet it can also be detrimental when it
persists long after a threat has passed. Flexibility of the fear response may be most …

Social neuroscience, the study of the neurobiological basis of social behavior, has become
a major area of current research in behavioral neuroscience and psychiatry, since many …

The medial prefrontal cortex and amygdala are involved in the regulation of social behavior
and associated with psychiatric diseases but their detailed neurophysiological mechanisms …

Background Prenatal exposure to infectious or inflammatory insults increases the risk of
neurodevelopmental disorders. Using a well-established mouse model of prenatal viral-like …