[HTML][HTML] m6A modification in inflammatory bowel disease provides new insights into clinical applications

J Zhang, B Song, Y Zeng, C Xu, L Gao, Y Guo… - Biomedicine & …, 2023 - Elsevier
Inflammatory bowel disease (IBD) results from a complex interplay between genetic
predisposition, environmental factors, and gut microbes. The role of N6-methyladenosine …

N6-Methyladenosine RNA modification in the tumor immune microenvironment: novel implications for immunotherapy

L Guo, H Yang, C Zhou, Y Shi, L Huang… - Frontiers in …, 2021 - frontiersin.org
N6-methyladenosine (m6A) methylation is one of the most common modifications of RNA in
eukaryotic cells, and is mainly regulated by m6A methyltransferases (writers), m6A …

Human umbilical cord mesenchymal stem cells derived exosome shuttling mir-129-5p attenuates inflammatory bowel disease by inhibiting ferroptosis

Z Wei, S Hang, DK Wiredu Ocansey, Z Zhang… - Journal of …, 2023 - Springer
Background Ferroptosis, a unique form of non-apoptotic cell death, is dependent on iron and
lipoperoxidation, and has been shown to be associated with the pathogenesis of …

METTL3 overexpression aggravates LPS-induced cellular inflammation in mouse intestinal epithelial cells and DSS-induced IBD in mice

L Yang, G Wu, Q Wu, L Peng, L Yuan - Cell Death Discovery, 2022 - nature.com
The inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative
colitis (UC), are chronic inflammatory disorders of the intestine. Dysregulated cytokine …

A broad m6A modification landscape in inflammatory bowel disease

K Nie, J Yi, Y Yang, M Deng, Y Yang… - Frontiers in cell and …, 2022 - frontiersin.org
Background and Aims: N6-Methyladenosine (m6A) is the most common post-transcriptional
modification on eukaryotic mRNA, affecting the mRNA's fate. The role of m6A regulation in …

The role of mesenchymal stem cell-derived exosome in epigenetic modifications in inflammatory diseases

Z Zhao, L Zhang, DKW Ocansey, B Wang… - Frontiers in …, 2023 - frontiersin.org
Epigenetic modification is a complex process of reversible and heritable alterations in gene
function, and the combination of epigenetic and metabolic alterations is recognized as an …

Implications of m6A methylation and microbiota interaction in non-small cell lung cancer: From basics to therapeutics

FS Qiu, JQ He, YS Zhong, MY Guo… - Frontiers in Cellular and …, 2022 - frontiersin.org
N6-methyladenine (m6A) is one of the most common RNA epigenetic modifications in all
higher eukaryotes. Increasing evidence demonstrated that m6A-related proteins, acted as …

Dietary High Glycinin Reduces Growth Performance and Impairs Liver and Intestinal Health Status of Orange-Spotted Grouper (Epinephelus coioides)

Y Yin, X Zhao, L Yang, K Wang, Y Sun, J Ye - Animals, 2023 - mdpi.com
Simple Summary Soy antigen proteins are regarded as the cause of fish enteritis, of which
glycinin is one of the main soy antigen proteins. By comparing different levels of glycinin …

Immune infiltration of ulcerative colitis and detection of the m6A subtype

C Gu, J Wu, W Zhang, Y Yao, W Yan… - Journal of …, 2022 - Wiley Online Library
Ulcerative colitis (UC) is an inflammatory bowel disease characterized by persistent colon
inflammation. N6‐methyladenosine (m6A) methylation is one of the most prevalent RNA …

The relationship between the network of non-coding RNAs-molecular targets and N6-methyladenosine modification in colorectal cancer

S Lu, X Ding, Y Wang, X Hu, T Sun, M Wei… - Frontiers in cell and …, 2021 - frontiersin.org
Recent accumulating researches implicate that non-coding RNAs (ncRNAs) including
microRNA (miRNA), circular RNA (circRNA), and long non-coding RNA (lncRNAs) play …