Congestive heart failure

MC Scott, ME Winters - Emergency Medicine Clinics, 2015 - emed.theclinics.com
Congestive heart failure (CHF) remains the most common reason for hospitalization in the
United States for people aged 65 years and older, with more than 1 million patients admitted …

Blocking the RAAS at different levels: an update on the use of the direct renin inhibitors alone and in combination

F Cagnoni, CAN Njwe, A Zaninelli… - Vascular health and …, 2010 - Taylor & Francis
The renin–angiotensin–aldosterone system (RAAS), an important regulator of blood
pressure and mediator of hypertension-related complications, is a prime target for …

Local angiotensin II aggravates cardiac remodeling in hypertension

J Xu, OA Carretero, TD Liao, H Peng… - American Journal …, 2010 - journals.physiology.org
Angiotensin II (ANG II) contributes to hypertension, cardiac hypertrophy, fibrosis, and
dysfunction; however, it is difficult to separate the cardiac effect of ANG II from its …

Recent changes in the landscape of combination RAS blockade

BJ Epstein, SM Smith, R Choksi - Expert review of cardiovascular …, 2009 - Taylor & Francis
The renin–angiotensin system (RAS) is a prime target for cardiovascular drug therapy.
Inhibition of the RAS lowers blood pressure and confers protection against cardiovascular …

[PDF][PDF] Cardiovascular effects of the combination of levosimendan and valsartan in hypertensive Dahl/Rapp rats

A Biala, P Finckenberg, A Korpi, M Loytainen… - Journal of Physiology …, 2011 - jpp.krakow.pl
Hypertension is the main risk factor for left ventricular hypertrophy and development of
diastolic heart failure. There is no yet treatment, which can effectively reduce mortality in …

[HTML][HTML] Enalapril improves endothelial function in patients with migraine: A randomized, double-blind, placebo-controlled trial

SH Javanmard, SA Sonbolestan… - Journal of Research …, 2011 - ncbi.nlm.nih.gov
BACKGROUND: There are increasing evidences of endothelial dysfunction in migraine. The
ACE-inhibitors have previously been shown to be effective in migraine prophylaxis …

[HTML][HTML] Detrimental effect of renin-angiotensin blockade on progression of chronic kidney disease at later stages: A matter of dosage adjustment?

F Caravaca-Fontán, J Valladares… - Nefrología (English …, 2020 - Elsevier
Introduction The renoprotective effect of renin-angiotensin (RAS) blockers (angiotensin
converting enzyme inhibitors and angiotensin receptor blockers) has been questioned in …

Significance of the renin-angiotensin system in clinical conditions

V Đambić, Đ Pojatić, A Stažić… - Selected Chapters from the …, 2020 - books.google.com
The renin-angiotensin system, in both its circulating and local tissue roles, is intertwined with
multiple other regulatory and signalling mechanisms in various tissues and organ systems. It …

Calcium Channel Blocker Enhances Beneficial Effects of an Angiotensin II AT1 Receptor Blocker against Cerebrovascular-Renal Injury in type 2 Diabetic Mice

K Rafiq, SJ Sherajee, H Hitomi, D Nakano, H Kobori… - Plos one, 2013 - journals.plos.org
Recent clinical trials have demonstrated that combination therapy with renin-angiotensin
system inhibitors plus calcium channel blockers (CCBs) elicits beneficial effects on …

[图书][B] Chronic kidney disease (CKD) and hypertension essentials

AS Bomback, GL Bakris - 2010 - books.google.com
The World's Leading Experts Provide all the'Essentials' Needed to Manage Patients in the
Office and on the Ward! Nearly 17% of adults in the United States have Chronic Kidney …