A detailed overview of SARS-CoV-2 omicron: its sub-variants, mutations and pathophysiology, clinical characteristics, immunological landscape, immune escape, and …

S Chatterjee, M Bhattacharya, S Nag, K Dhama… - Viruses, 2023 - mdpi.com
The COVID-19 pandemic has created significant concern for everyone. Recent data from
many worldwide reports suggest that most infections are caused by the Omicron variant and …

Molecular characteristics, immune evasion, and impact of SARS-CoV-2 variants

C Sun, C Xie, GL Bu, LY Zhong, MS Zeng - Signal Transduction and …, 2022 - nature.com
The persistent COVID-19 pandemic since 2020 has brought an enormous public health
burden to the global society and is accompanied by various evolution of the virus genome …

Real-world effectiveness of early molnupiravir or nirmatrelvir–ritonavir in hospitalised patients with COVID-19 without supplemental oxygen requirement on admission …

CKH Wong, ICH Au, KTK Lau, EHY Lau… - The Lancet Infectious …, 2022 - thelancet.com
Background Data on the effectiveness of oral antivirals in patients with mild-to-moderate
COVID-19 are urgently needed. This retrospective cohort study aimed to evaluate the …

Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19

H Xu, S Li, J Liu, J Cheng, L Kang… - Proceedings of the …, 2023 - National Acad Sciences
The coronavirus disease 2019 (COVID-19) pandemic is an ongoing global health concern,
and effective antiviral reagents are urgently needed. Traditional Chinese medicine theory …

Small molecules in the treatment of COVID-19

S Lei, X Chen, J Wu, X Duan, K Men - Signal transduction and targeted …, 2022 - nature.com
The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …

Impact of the use of oral antiviral agents on the risk of hospitalization in community coronavirus disease 2019 patients (COVID-19)

TCF Yip, GCY Lui, MSM Lai, VWS Wong… - Clinical infectious …, 2023 - academic.oup.com
Background We examined the effectiveness of molnupiravir and nirmatrelvir/ritonavir in
reducing hospitalization and deaths in a real-world cohort of nonhospitalized patients with …

Recent review of COVID-19 management: Diagnosis, treatment and vaccination

VP Chavda, S Vuppu, T Mishra, S Kamaraj… - Pharmacological …, 2022 - Springer
The idiopathic Coronavirus disease 2019 (COVID-19) pandemic outbreak caused by the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has reached global …

Efficacy and safety of Paxlovid for COVID-19: a meta-analysis

Q Zheng, P Ma, M Wang, Y Cheng, M Zhou… - Journal of …, 2023 - journalofinfection.com
We read with interest the manuscript “Sensitivity and specificity of surveillance case
definitions in detection of influenza and respiratory syncytial virus among hospitalized …

[HTML][HTML] Real-world experience with available, outpatient COVID-19 therapies in solid organ transplant recipients during the omicron surge

C Radcliffe, CF Palacios, MM Azar, E Cohen… - American Journal of …, 2022 - Elsevier
The SARS-CoV-2 pandemic continues to place a substantial burden on healthcare systems.
Outpatient therapies for mild-to-moderate disease have reduced hospitalizations and deaths …

Strategies for the development and approval of COVID-19 vaccines and therapeutics in the post-pandemic period

D Ao, X He, J Liu, L Xu - Signal Transduction and Targeted Therapy, 2023 - nature.com
The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted
in significant casualties and put immense strain on public health systems worldwide, leading …