EBV and apoptosis: the viral master regulator of cell fate?

L Fitzsimmons, GL Kelly - Viruses, 2017 - mdpi.com
Epstein–Barr virus (EBV) was first discovered in cells from a patient with Burkitt lymphoma
(BL), and is now known to be a contributory factor in 1–2% of all cancers, for which there are …

An Epstein-Barr virus microRNA blocks interleukin-1 (IL-1) signaling by targeting IL-1 receptor 1

CM Skinner, NS Ivanov, SA Barr, Y Chen… - Journal of …, 2017 - Am Soc Microbiol
Epstein-Barr virus (EBV) encodes> 44 viral microRNAs (miRNAs) that are differentially
expressed throughout infection, can be detected in Epstein-Barr virus (EBV)-positive tumors …

Argonaute CLIP-Seq reveals miRNA targetome diversity across tissue types

PM Clark, P Loher, K Quann, J Brody, ER Londin… - Scientific reports, 2014 - nature.com
To date, analyses of individual targets have provided evidence of a miRNA targetome that
extends beyond the boundaries of messenger RNAs (mRNAs) and can involve non-Watson …

Tiny giants of gene regulation: experimental strategies for microRNA functional studies

BR Steinkraus, M Toegel… - Wiley Interdisciplinary …, 2016 - Wiley Online Library
The discovery over two decades ago of short regulatory microRNAs (miRNAs) has led to the
inception of a vast biomedical research field dedicated to understanding these powerful …

MBSTAR: multiple instance learning for predicting specific functional binding sites in microRNA targets

S Bandyopadhyay, D Ghosh, R Mitra, Z Zhao - Scientific reports, 2015 - nature.com
MicroRNA (miRNA) regulates gene expression by binding to specific sites in the 3′
untranslated regions of its target genes. Machine learning based miRNA target prediction …

Epstein-Barr virus microRNAs regulate B cell receptor signal transduction and lytic reactivation

Y Chen, D Fachko, NS Ivanov, CM Skinner… - PLoS …, 2019 - journals.plos.org
MicroRNAs (miRNAs) are post-transcriptional regulatory RNAs that can modulate cell
signaling and play key roles in cell state transitions. Epstein-Barr virus (EBV) expresses> 40 …

Global identification of functional microRNA-mRNA interactions in Drosophila

HH Wessels, S Lebedeva, A Hirsekorn… - Nature …, 2019 - nature.com
MicroRNAs (miRNAs) are key mediators of post-transcriptional gene expression silencing.
So far, no comprehensive experimental annotation of functional miRNA target sites exists in …

miRNA-dependent activation of mRNA translation

WJ Ni, XM Leng - Microrna, 2016 - ingentaconnect.com
MicroRNAs (miRNAs) are small and important RNA molecules. They can regulate gene
expression at different levels. Although their biogenesis has been well documented …

TargetNet: functional microRNA target prediction with deep neural networks

S Min, B Lee, S Yoon - Bioinformatics, 2022 - academic.oup.com
Motivation MicroRNAs (miRNAs) play pivotal roles in gene expression regulation by binding
to target sites of messenger RNAs (mRNAs). While identifying functional targets of miRNAs …

Multiple viral microRNAs regulate interferon release and signaling early during infection with Epstein-Barr virus

M Bouvet, S Voigt, T Tagawa, M Albanese, YFA Chen… - MBio, 2021 - Am Soc Microbiol
ABSTRACT Epstein-Barr virus (EBV), a human herpesvirus, encodes 44 microRNAs
(miRNAs), which regulate many genes with various functions in EBV-infected cells. Multiple …