Small RNA targets: advances in prediction tools and high-throughput profiling
Simple Summary MicroRNAs (miRNAs) are a category of small RNAs (sRNAs) that have
been found to regulate gene expression. Through the mediation of proteins from the …
been found to regulate gene expression. Through the mediation of proteins from the …
MiRNA fine tuning for crop improvement: using advance computational models and biotechnological tools
MiRNAs modulate target genes expression at post-transcriptional levels, by reducing spatial
abundance of mRNAs. MiRNAs regulats plant metabolism, and emerged as regulators of …
abundance of mRNAs. MiRNAs regulats plant metabolism, and emerged as regulators of …
MicroRNA target prediction tools for animals: Where we are at and where we are going to-A systematic review
RMMW Feitosa, P Prieto-Oliveira, H Brentani… - … Biology and Chemistry, 2022 - Elsevier
MicroRNAs (miRNAs) are non-coding RNAs containing 19–26 nucleotides, and they directly
regulate the translation of mRNAs by binding to them. MiRNAs participate in various …
regulate the translation of mRNAs by binding to them. MiRNAs participate in various …
MicroRNA-focused CRISPR/Cas9 screen identifies miR-142 as a key regulator of Epstein-Barr virus reactivation
Y Chen, RP Kincaid, K Bastin, DN Fachko… - PLoS …, 2024 - journals.plos.org
Reactivation from latency plays a significant role in maintaining persistent lifelong Epstein-
Barr virus (EBV) infection. Mechanisms governing successful activation and progression of …
Barr virus (EBV) infection. Mechanisms governing successful activation and progression of …
Comprehensive machine-learning-based analysis of microRNA–target interactions reveals variable transferability of interaction rules across species
G Ben Or, I Veksler-Lublinsky - BMC bioinformatics, 2021 - Springer
Background MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene
expression post-transcriptionally via base-pairing with complementary sequences on …
expression post-transcriptionally via base-pairing with complementary sequences on …
[HTML][HTML] RNA-bioinformatics: tools, services and databases for the analysis of RNA-based regulation
The importance of RNA-based regulation is becoming more and more evident. Genome-
wide sequencing efforts have shown that the majority of the DNA in eukaryotic genomes is …
wide sequencing efforts have shown that the majority of the DNA in eukaryotic genomes is …
Literature review of baseline information to support the risk assessment of RNA i‐based GM plants
J Paces, M Nic, T Novotny… - EFSA Supporting …, 2017 - Wiley Online Library
This report is the outcome of an EFSA procurement aiming at investigating and summarising
the state of knowledge on (I) the mode-of-action of dsRNA and miRNA pathways,(II) the …
the state of knowledge on (I) the mode-of-action of dsRNA and miRNA pathways,(II) the …
An ensemble svm model for the accurate prediction of non-canonical microrna targets
Background MicroRNAs are small non-coding endogenous RNAs that are responsible for
post-transcriptional regulation of genes. Given that large numbers of human genes are …
post-transcriptional regulation of genes. Given that large numbers of human genes are …
[HTML][HTML] Advanced computational predictive models of miRNA-mRNA interaction efficiency
S Bader, T Tuller - Computational and Structural Biotechnology Journal, 2024 - Elsevier
The modeling of miRNA-mRNA interactions holds significant implications for synthetic
biology and human health. However, this research area presents specific challenges due to …
biology and human health. However, this research area presents specific challenges due to …
A high-throughput 3'UTR reporter screening identifies microRNA interactomes of cancer genes
G Van Peer, E Mets, S Claeys, I De Punt, S Lefever… - PLoS …, 2018 - journals.plos.org
Introduction Despite the established contribution of deregulated microRNA (miRNA) function
to carcinogenesis, relatively few miRNA-cancer gene interactions have been validated …
to carcinogenesis, relatively few miRNA-cancer gene interactions have been validated …