The role and impact of abnormal vitamin levels in autism spectrum disorders

J Cui, Z Zhai, S Wang, X Song, T Qiu, L Yu, Q Zhai… - Food & Function, 2024 - pubs.rsc.org
The prevalence of autism spectrum disorder (ASD), a neurodevelopmental disorder with a
predominance of social behavioral disorders, has increased dramatically in various …

Efficacy of Nano-Based Strategies on the Safe Delivery and Bioavailability of Vitamin D

M Hussain, J Xu, I Ahmad, K Hussain… - Food Reviews …, 2023 - Taylor & Francis
Vitamin D is an essential micronutrient; it is necessary for human well-being, including brain
and heart health; its deficiency is widespread and can lead to fatal diseases. Daily …

[HTML][HTML] Safety Profile of Vitamin D in Italy: An Analysis of Spontaneous Reports of Adverse Reactions Related to Drugs and Food Supplements

V Maggini, G Crescioli, I Ippoliti, E Gallo… - Journal of Clinical …, 2023 - mdpi.com
Vitamin D (VitD) is largely used in Italy, often inappropriately; thus, an evaluation of its safety
is a crucial issue. This study analyses the adverse reactions (ARs) associated with the use of …

Development, optimization, and evaluation of Empagliflozin nanoemulsion for the management of neuroinflammation associated Alzheimer's disease

NA Alhakamy, EA Aljehani, AB Abdel-Naim… - Journal of Drug Delivery …, 2024 - Elsevier
Alzheimer's disease (AD) is one of the most pervasive and progressive neurodegenerative
disorders. Recently, empagliflozin (EMPA) has been reported as a potent anti-inflammatory …

Tannic acid coated nanosuspension for oral delivery of chrysin intended for anti-schizophrenic effect in mice

A Salama, AH Salama, MH Asfour - International Journal of Pharmaceutics, 2024 - Elsevier
Chrysin is a flavonoid drug with numerous therapeutic activities. It suffers from low intestinal
absorption owing to its hydrophobicity. Therefore, the aim of this study is to exploit the …

Revisiting the significance of nano-vitamin D for food fortification and therapeutic application

GK Jain, V Raina, R Grover, J Sharma… - Drug Development …, 2024 - Taylor & Francis
Objective Vitamin D (a prohormone) is an important micronutrient required by the body for
skeletal homeostasis and a range of non-skeletal actions. Calcitriol, the active form of …

A Comparison and Safety Evaluation of Micellar versus Standard Vitamin D3 Oral Supplementation in a Randomized, Double-Blind Human Pilot Study

J Solnier, C Chang, Y Zhang, YC Kuo, M Du, YS Roh… - Nutrients, 2024 - mdpi.com
The aim of this pilot study was to evaluate and compare bioavailability and safety of two
Vitamin D3 formulations (softgels) in healthy adults, at single daily doses of 1000 and 2500 …

Luminescent Alendronic Acid-Conjugated Micellar Nanostructures for Potential Application in the Bone-Targeted Delivery of Cholecalciferol

F Rizzi, A Panniello, R Comparelli, I Arduino, E Fanizza… - Molecules, 2024 - mdpi.com
Vitamin D, an essential micronutrient crucial for skeletal integrity and various non-skeletal
physiological functions, exhibits limited bioavailability and stability in vivo. This study is …

Revolutionizing nanomedicine: Expanding horizons of nanoemulsions in drug delivery and beyond

M Kumar, N Chauhan, D Kumar… - Journal of Dispersion …, 2024 - Taylor & Francis
Nanoemulsions are nano-sized particles, typically ranging from tens to hundreds of
nanometers. These nanoemulsions possess various appealing properties, making them …

Nutraceutically-enhanced oral delivery of vitamin D3 via Bio-SNEDDS: Demonstrating in vivo superiority over pediatric formulations

M Kazi, F Almarri, AAW Shahba, A Ahmad… - Biochemical and …, 2024 - Elsevier
Abstract Background Vitamin D3 (VD3) deficiency among children in Saudi Arabia remains
a pressing concern due to its poor bioavailability and the limitations of current pediatric …