Interactions between cisplatin and quercetin at physiological and hyperthermic conditions on cancer cells in vitro and in vivo

N Oršolić, D Odeh, MJ Jembrek, J Knežević, D Kučan - Molecules, 2020 - mdpi.com
Quercetin (QU), a hyperthermic sensitizer, when combined with cisplatin (CP) affects tumor
growth. To determine the effects of QU and CP and their interactions, multimodal treatment …

Exploration of potential targets and mechanisms of fisetin in the treatment of non‐small‐cell lung carcinoma via network pharmacology and in vitro validation

J Ling, Y Wang, L Ma, A Chang… - Evidence‐Based …, 2022 - Wiley Online Library
Purpose. The morbidity and fatality rates of non‐small‐cell lung cancer (NSCLC) were high,
although a combination of multiple treatments was used. Fisetin, a small flavonoid …

A network pharmacological approach to reveal the pharmacological targets and its associated biological mechanisms of prunetin-5-o-glucoside against gastric cancer

P Vetrivel, R Murugesan, PB Bhosale, SE Ha, HH Kim… - Cancers, 2021 - mdpi.com
Simple Summary Identification of pharmacological targets in cancer provides a major
walkthrough toward treatment strategies. The present research adopted a network …

Fisetin Alleviates Neointimal Hyperplasia via PPARγ/PON2 Antioxidative Pathway in SHR Rat Artery Injury Model

F Pei, H Pei, C Su, L Du, J Wang, F Xie… - Oxidative Medicine …, 2021 - Wiley Online Library
The phenotypic transformation of proliferation and migration in vascular smooth muscle cells
(VSMCs) from media to intima is the basic pathology of neointimal hyperplasia after …

The protective effects of juglanin in cerebral ischemia reduce blood–brain barrier permeability via inhibition of VEGF/VEGFR2 signaling

J Liu, L Chen, X Zhang, L Pan… - Drug Design, Development …, 2020 - Taylor & Francis
Introduction Ischemic brain injury due to stroke or other pathologies is a major contributor to
disability and mortality worldwide. Upon the occurrence of stroke, neuronal cells undergo …

Assessment of the physicochemical and sensory characteristics of fermented camel milk fortified with Cordia myxa and its biological effects against oxidative stress …

ESH Atwaa, MR Shahein, E Raya-Álvarez… - Frontiers in …, 2023 - frontiersin.org
Natural feed additives and their potential benefits in production of safe and highly nutritious
food have gained the attention of many researchers the last decades. Cordia myxa is a …

Molecular insights into potential contributions of natural polyphenols to lung cancer treatment

Q Zhou, H Pan, J Li - Cancers, 2019 - mdpi.com
Naturally occurring polyphenols are believed to have beneficial effects in the prevention and
treatment of a myriad of disorders due to their anti-inflammatory, antioxidant, antineoplastic …

Natural substances derived from herbs or plants are promising sources of anticancer agents against colorectal cancer via triggering apoptosis

ZB Liu, T Zhang, X Ye, ZQ Liu, X Sun… - Journal of Pharmacy …, 2022 - academic.oup.com
Objectives Nowadays, one of the most common gastrointestinal cancers is colorectal cancer
(CRC). Chemotherapy is still one of the main methods to treat cancer. However, the currently …

Renewable Electroconductive Hydrogels for Accelerated Diabetic Wound Healing and Motion Monitoring

XQ Hu, JZ Zhu, Z Hao, L Tang, J Sun, WR Sun… - …, 2024 - ACS Publications
Diabetic foot ulcers (DFUs), a prevalent complication of diabetes mellitus, may result in an
amputation. Natural and renewable hydrogels are desirable materials for DFU dressings …

[HTML][HTML] Cholinesterase inhibitory potential of quercetin towards Alzheimer's disease-a promising natural molecule or fashion of the day?-A narrowed review

IE Orhan - Current Neuropharmacology, 2021 - ncbi.nlm.nih.gov
Natural substances are known to have strong protective effects against neurodegenerative
diseases. Among them, phenolic compounds, especially flavonoids, come to the fore with …