SARS-CoV-2-specific immune response and the pathogenesis of COVID-19

E Gusev, A Sarapultsev, L Solomatina… - International journal of …, 2022 - mdpi.com
The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …

[HTML][HTML] Circulating microRNAs as emerging regulators of COVID-19

Y Liang, D Fang, X Gao, X Deng, N Chen, J Wu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19), an infectious disease caused by the novel
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global pandemic that …

The role of exosomes in inflammatory diseases and tumor-related inflammation

Y Tian, C Cheng, Y Wei, F Yang, G Li - Cells, 2022 - mdpi.com
Inflammation plays a decisive role in inducing tumorigenesis, promoting tumor development,
tumor invasion and migration. The interaction of cancer cells with their surrounding stromal …

Avenanthramide C from oats protects pyroptosis through dependent ROS-induced mitochondrial damage by PI3K ubiquitination and phosphorylation in pediatric …

Z Pu, C Shen, W Zhang, H Xie… - Journal of Agricultural and …, 2022 - ACS Publications
Oat containing rich β-glucan, polyphenols, flavonoids, saponins, alkaloids, and other
substances shows good biological activities. Therefore, the present study aimed to uncover …

Inflammasomes as biomarkers and therapeutic targets in traumatic brain injury and related-neurodegenerative diseases: A comprehensive overview

D Kattan, C Barsa, S Mekhijian, Z Shakkour… - Neuroscience & …, 2023 - Elsevier
Given the ambiguity surrounding traumatic brain injury (TBI) pathophysiology and the lack of
any Food and Drug Administration (FDA)-approved neurotherapeutic drugs, there is an …

Integrated miRNA/cytokine/chemokine profiling reveals severity-associated step changes and principal correlates of fatality in COVID-19

JC Wilson, D Kealy, SR James, T Plowman, K Newling… - IScience, 2022 - cell.com
Inflammatory cytokines and chemokines (CC) drive COVID-19 pathology. Yet, patients with
similar circulating CC levels present with different disease severity. Here, we determined …

Micro-players of great significance—host microRNA signature in viral infections in humans and animals

E Ostrycharz, B Hukowska-Szematowicz - International Journal of …, 2022 - mdpi.com
Over time, more and more is becoming known about micro-players of great significance.
This is particularly the case for microRNAs (miRNAs; miR), which have been found to …

Human bone marrow mesenchymal stem cell-derived extracellular vesicles reduce inflammation and pyroptosis in acute kidney injury via miR-223-3p/HDAC2/SNRK

Z Xie, J Tang, Z Chen, L Wei, J Chen, Q Liu - Inflammation Research, 2023 - Springer
Objective Bone marrow mesenchymal stem cell (BMSC)-derived extracellular vesicles (EVs)
have been demonstrated as a potential therapeutic agent in acute kidney injury (AKI) …

The biomarkers' landscape of post-COVID-19 patients can suggest selective clinical interventions

D Paris, L Palomba, MC Albertini, A Tramice, L Motta… - Scientific Reports, 2023 - nature.com
In COVID-19 clinical symptoms can persist even after negativization also in individuals who
have had mild or moderate disease. We here investigated the biomarkers that define the …

Non-canonical inflammasome pathway: The role of cell death and inflammation in Ehrlichiosis

AK Sharma, N Ismail - Cells, 2023 - mdpi.com
Activating inflammatory caspases and releasing pro-inflammatory mediators are two
essential functions of inflammasomes which are triggered in response to pathogen …