Monocytes mediate HIV neuropathogenesis: mechanisms that contribute to HIV associated neurocognitive disorders

DW Williams, M Veenstra, PJ Gaskill… - Current HIV …, 2014 - ingentaconnect.com
HIV infected people are living longer due to the success of combined antiretroviral therapy
(cART). However, greater than 40-70% of HIV infected individuals develop HIV associated …

Recent advances in plasma-engineered polymers for biomarker-based viral detection and highly multiplexed analysis

SM Mousavi, SA Hashemi, MY Kalashgrani, A Gholami… - Biosensors, 2022 - mdpi.com
Infectious diseases remain a pervasive threat to global and public health, especially in many
countries and rural urban areas. The main causes of such severe diseases are the lack of …

Compartmentalized replication of R5 T cell-tropic HIV-1 in the central nervous system early in the course of infection

CB Sturdevant, SB Joseph, G Schnell, RW Price… - PLoS …, 2015 - journals.plos.org
Compartmentalized HIV-1 replication within the central nervous system (CNS) likely
provides a foundation for neurocognitive impairment and a potentially important tissue …

HIV-associated neurocognitive disorder

RC Smail, BJ Brew - Handbook of clinical neurology, 2018 - Elsevier
Human immunodeficiency virus (HIV)-associated neurocognitive disorder (HAND) affects
roughly half the HIV-positive population. The symptoms of cognitive slowing, poor …

Cerebrospinal fluid (CSF) neuronal biomarkers across the spectrum of HIV infection: hierarchy of injury and detection

J Peterson, M Gisslen, H Zetterberg, D Fuchs… - PloS one, 2014 - journals.plos.org
The character of central nervous system (CNS) HIV infection and its effects on neuronal
integrity vary with evolving systemic infection. Using a cross-sectional design and archived …

Neurochemical biomarkers to study CNS effects of COVID‐19: A narrative review and synthesis

A Edén, J Simrén, RW Price… - Journal of …, 2021 - Wiley Online Library
Neurological symptoms are frequently reported in patients suffering from COVID‐19.
Common CNS‐related symptoms include anosmia, caused by viral interaction with either …

Disturbed amino acid metabolism in HIV: association with neuropsychiatric symptoms

JM Gostner, K Becker, K Kurz, D Fuchs - Frontiers in psychiatry, 2015 - frontiersin.org
Blood levels of the amino acid phenylalanine, as well as of the tryptophan breakdown
product kynurenine, are found to be elevated in human immunodeficiency virus type 1 (HIV …

Role of HIV in amyloid metabolism

M Ortega, BM Ances - Journal of Neuroimmune Pharmacology, 2014 - Springer
HIV infection has changed from an acute devastating disease to a more chronic illness due
to combination anti-retroviral treatment (cART). In the cART era, the life expectancy of HIV …

Imaging correlates of the blood–brain barrier disruption in HIV-associated neurocognitive disorder and therapeutic implications

J Chaganti, K Marripudi, LP Staub, CD Rae, TM Gates… - Aids, 2019 - journals.lww.com
Objective: HIV-associated neurocognitive disorders (HANDs) in the context of suppressive
combination antiretroviral therapy (cART) still occur. We explored the role of blood–brain …

Neuropathogenesis of human immunodeficiency virus infection

B Sillman, C Woldstad, J Mcmillan… - Handbook of clinical …, 2018 - Elsevier
Human immunodeficiency virus (HIV)-associated neurocognitive disorders (HAND) remain a
common end-organ manifestation of viral infection. Subclinical and mild symptoms lead to …