T van Gelder - Kidney International, 2021 - Elsevier
The most frequently used immunosuppressive treatment in kidney transplant recipients is the combination therapy of a calcineurin inhibitor and mycophenolate mofetil (MMF), with or …
L Paniagua-González, E Lendoiro… - … of Pharmaceutical and …, 2022 - Elsevier
Therapeutic drug monitoring (TDM) of immunosuppressants is essential to avoid either rejection or toxicity after solid organ transplantations. Capillary microsampling approaches …
TC Zwart, E Metscher… - British Journal of …, 2022 - Wiley Online Library
Aims Immunosuppressant and kidney function monitoring are crucial for kidney transplant recipient follow‐up. Microsamples enable remote sampling and minimise patient burden as …
Therapeutic drug monitoring of mycophenolic acid (MPA) based on area under the curve (AUC) is well‐established and machine learning (ML) approaches could help to estimate …
M Kantauskaite, L Müller, J Hillebrandt… - Clinical …, 2022 - Wiley Online Library
Modification of vaccination strategies is necessary to improve the immune response to SARS‐CoV‐2 vaccination in kidney transplant recipients (KTRs). This multicenter …
F Lemaitre, K Budde, T Van Gelder… - Therapeutic Drug …, 2022 - journals.lww.com
Nirmatrelvir/ritonavir (Paxlovid®) consists of a peptidomimetic inhibitor (Nirmatrelvir) of the SARS-CoV-2 main protease and a pharmacokinetic enhancer (Ritonavir). It is approved for …
M Resztak, J Sobiak, A Czyrski - Pharmaceutics, 2021 - mdpi.com
The review includes studies dated 2011–2021 presenting the newest information on voriconazole (VCZ), mycophenolic acid (MPA), and vancomycin (VAN) therapeutic drug …
Immunosuppressive drugs have been key to the success of liver transplantation and are essential components of the treatment of inflammatory bowel disease (IBD) and autoimmune …
A Kocur, T Pawiński - International Journal of Molecular Sciences, 2022 - mdpi.com
Miniaturisation and simplification are novel approaches in clinical bioanalysis, especially in therapeutic drug monitoring (TDM). These contemporary trends are related to the sampling …