[HTML][HTML] Increased memory B cell potency and breadth after a SARS-CoV-2 mRNA boost
The Omicron variant of SARS-CoV-2 infected many vaccinated and convalescent
individuals,–. Despite the reduced protection from infection, individuals who received three …
individuals,–. Despite the reduced protection from infection, individuals who received three …
[HTML][HTML] Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron
Summary The SARS-CoV-2 Omicron variant with increased fitness is spreading rapidly
worldwide. Analysis of cryo-EM structures of the spike (S) from Omicron reveals amino acid …
worldwide. Analysis of cryo-EM structures of the spike (S) from Omicron reveals amino acid …
[HTML][HTML] Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule, in healthy adults: interim results from two single …
G Zeng, Q Wu, H Pan, M Li, J Yang, L Wang… - The Lancet Infectious …, 2022 - thelancet.com
Background Large-scale vaccination against COVID-19 is being implemented in many
countries with CoronaVac, an inactivated vaccine. We aimed to assess the immune …
countries with CoronaVac, an inactivated vaccine. We aimed to assess the immune …
[HTML][HTML] Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants
Abstract Omicron (B. 1.1. 529), the most heavily mutated SARS-CoV-2 variant so far, is
highly resistant to neutralizing antibodies, raising concerns about the effectiveness of …
highly resistant to neutralizing antibodies, raising concerns about the effectiveness of …
[HTML][HTML] Robust induction of B cell and T cell responses by a third dose of inactivated SARS-CoV-2 vaccine
Y Liu, Q Zeng, C Deng, M Li, L Li, D Liu, M Liu, X Ruan… - Cell discovery, 2022 - nature.com
SARS-CoV-2 inactivated vaccines have shown remarkable efficacy in clinical trials,
especially in reducing severe illness and casualty. However, the waning of humoral …
especially in reducing severe illness and casualty. However, the waning of humoral …
[HTML][HTML] Heterologous immunization with inactivated vaccine followed by mRNA-booster elicits strong immunity against SARS-CoV-2 Omicron variant
F Zuo, H Abolhassani, L Du, A Piralla… - Nature …, 2022 - nature.com
The recent emergence of the Omicron variant has raised concerns on vaccine efficacy and
the urgent need to study more efficient vaccination strategies. Here we observed that an …
the urgent need to study more efficient vaccination strategies. Here we observed that an …
[HTML][HTML] Omicron-specific mRNA vaccination alone and as a heterologous booster against SARS-CoV-2
The Omicron variant of SARS-CoV-2 recently swept the globe and showed high level of
immune evasion. Here, we generate an Omicron-specific lipid nanoparticle (LNP) mRNA …
immune evasion. Here, we generate an Omicron-specific lipid nanoparticle (LNP) mRNA …
[HTML][HTML] Considerations for the feasibility of neutralizing antibodies as a surrogate endpoint for COVID-19 vaccines
J Liu, Q Mao, X Wu, Q He, L Bian, Y Bai… - Frontiers in …, 2022 - frontiersin.org
To effectively control and prevent the pandemic of coronavirus disease 2019 (COVID-19),
suitable vaccines have been researched and developed rapidly. Currently, 31 COVID-19 …
suitable vaccines have been researched and developed rapidly. Currently, 31 COVID-19 …
[HTML][HTML] Recognition of variants of concern by antibodies and T cells induced by a SARS-CoV-2 inactivated vaccine
F Melo-González, JA Soto, LA González… - Frontiers in …, 2021 - frontiersin.org
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus
responsible of the current pandemic ongoing all around the world. Since its discovery in …
responsible of the current pandemic ongoing all around the world. Since its discovery in …
[HTML][HTML] Distinct conformations of SARS-CoV-2 Omicron spike protein and its interaction with ACE2 and antibody
Since November 2021, Omicron has been the dominant severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) variant that causes the coronavirus disease 2019 (COVID-19) …
coronavirus 2 (SARS-CoV-2) variant that causes the coronavirus disease 2019 (COVID-19) …