When identifying differentially expressed genes between two conditions using human
population RNA-seq samples, we found a phenomenon by permutation analysis: two …

Tumor progression and the efficacy of immunotherapy are strongly influenced by the
composition and abundance of immune cells in the tumor microenvironment. Due to the …

Abstract The Catalogue Of Somatic Mutations In Cancer (COSMIC), https://cancer. sanger.
ac. uk/cosmic, is an expert-curated knowledgebase providing data on somatic variants in …

Medical artificial intelligence (AI) systems have been remarkably successful, even
outperforming human performance at certain tasks. There is no doubt that AI is important to …

Computational pathology can lead to saving human lives, but models are annotation hungry
and pathology images are notoriously expensive to annotate. Self-supervised learning has …

The adoption of digital pathology has enabled the curation of large repositories of gigapixel
whole-slide images (WSIs). Computationally identifying WSIs with similar morphologic …

Mutation-induced activation of WNT–β-catenin signalling is a frequent driver event in human
cancer. Sustained WNT–β-catenin pathway activation endows cancer cells with sustained …

To study complex biological processes holistically, it is imperative to take an integrative
approach that combines multi-omics data to highlight the interrelationships of the involved …

Abstract Vision Transformers (ViTs), with the magnificent potential to unravel the information
contained within images, have evolved as one of the most contemporary and dominant …

Precision medicine is an emerging approach to clinical research and patient care that
focuses on understanding and treating disease by integrating multi-modal or multi-omics …