Antibiotic allergy

KG Blumenthal, JG Peter, JA Trubiano, EJ Phillips - The Lancet, 2019 - thelancet.com
Antibiotics are the commonest cause of life-threatening immune-mediated drug reactions
that are considered off-target, including anaphylaxis, and organ-specific and severe …

Evaluation and management of penicillin allergy: a review

ES Shenoy, E Macy, T Rowe, KG Blumenthal - Jama, 2019 - jamanetwork.com
Importance β-Lactam antibiotics are among the safest and most effective antibiotics. Many
patients report allergies to these drugs that limit their use, resulting in the use of broad …

[PDF][PDF] Drug allergy: a 2022 practice parameter update

DA Khan, A Banerji, KG Blumenthal, EJ Phillips… - Journal of Allergy and …, 2022 - Elsevier
Resolving conflict of interest The Joint Task Force on Practice Parameters (JTFPP) is
committed to ensuring that all guidelines are based on the best scientific evidence at the …

Efficacy of a clinical decision rule to enable direct oral challenge in patients with low-risk penicillin allergy: the PALACE randomized clinical trial

AM Copaescu, S Vogrin, F James… - JAMA internal …, 2023 - jamanetwork.com
Importance Fewer than 5% of patients labeled with a penicillin allergy are truly allergic. The
standard of care to remove the penicillin allergy label in adults is specialized testing …

Update on the adverse effects of antimicrobial therapies in community practice

S Mohsen, JA Dickinson, R Somayaji - Canadian Family Physician, 2020 - cfp.ca
Objective To gather information about antibiotic side effects to be used as a reference and
learning resource for prescribing physicians. Quality of evidence A search of websites of …

Penicillin allergy

M Castells, DA Khan, EJ Phillips - New England Journal of …, 2019 - Mass Medical Soc
Penicillin Allergy Many more patients are labeled as penicillin-allergic than actually are
allergic. The label should be analyzed with skin testing and test exposure. Patients with true …

Development and validation of a penicillin allergy clinical decision rule

JA Trubiano, S Vogrin, KYL Chua, J Bourke… - JAMA internal …, 2020 - jamanetwork.com
Importance Penicillin allergy is a significant public health issue for patients, antimicrobial
stewardship programs, and health services. Validated clinical decision rules are urgently …

The challenge of de‐labeling penicillin allergy

CA Stone Jr, J Trubiano, DT Coleman, CRF Rukasin… - Allergy, 2020 - Wiley Online Library
Abstract Background Even though 8%‐25% of most populations studied globally are labeled
as penicillin allergic, most diagnoses of penicillin allergy are made in childhood and relate …

[HTML][HTML] Sexually transmitted infections treatment guidelines, 2021

KA Workowski - MMWR. Recommendations and Reports, 2021 - cdc.gov
These guidelines for the treatment of persons who have or are at risk for sexually transmitted
infections (STIs) were updated by CDC after consultation with professionals knowledgeable …

The penicillin allergy delabeling program: a multicenter whole-of-hospital health services intervention and comparative effectiveness study

KYL Chua, S Vogrin, S Bury, A Douglas… - Clinical infectious …, 2021 - academic.oup.com
Background Penicillin allergies are associated with inferior patient and antimicrobial
stewardship outcomes. We implemented a whole-of-hospital program to assess the efficacy …