Type 2 and Non-type 2 Inflammation in the Upper Airways: Cellular and Molecular Alterations in Olfactory Neuroepithelium Cell Populations

C Marin, I Alobid, M López-Chacón… - Current Allergy and …, 2024 - Springer
Abstract Purpose of Review Neurogenesis occurring in the olfactory epithelium is critical to
continuously replace olfactory neurons to maintain olfactory function, but is impaired during …

Platelet-Rich Plasma (PRP) in the Treatment of Long COVID Olfactory Disorders: A Comprehensive Review

A Maniaci, S Lavalle, E Masiello, JR Lechien, L Vaira… - Biomedicines, 2024 - mdpi.com
Background: Long COVID has brought numerous challenges to healthcare, with olfactory
dysfunction (OD) being a particularly distressing outcome for many patients. The persistent …

SARS-CoV-2 immunity

A Bertoletti - Cellular & Molecular Immunology, 2024 - nature.com
Four years have swiftly passed since the identification of a novel coronavirus from patients
with pneumonia that signs the start of the COVID-19 pandemic [1]. The world's social and …

Histochemical Evidence for Reduced Immune Response in Nasal Mucosa of Patients with COVID-19

N Power Guerra, M Bierkämper, J Pablik… - International Journal of …, 2024 - mdpi.com
The primary entry point of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
is the nasal mucosa, where viral-induced inflammation occurs. When the immune response …

Persistent Neurological Deficits in Mouse PASC Reveal Antiviral Drug Limitations

AK Verma, S Lowery, LC Lin, E Duraisami… - bioRxiv, 2024 - biorxiv.org
Post-Acute Sequelae of COVID-19 (PASC) encompasses persistent neurological symptoms,
including olfactory and autonomic dysfunction. Here, we report chronic neurological …

[HTML][HTML] Persistent Smell Disorders After COVID-19 Infection and Their Impact on Quality of Life

YA Fageeh, AS Altuwaireqi, AB Alghuraibi, MS Alotaibi… - Cureus, 2024 - ncbi.nlm.nih.gov
Background The COVID-19 pandemic has led to various health challenges, including the
disruption of people's sense of smell. Olfactory disorders have been reported as a lingering …

Revealing the Hidden Impacts: Insights into Biological Aging and Long-Term Effects in Pauci-and Asymptomatic COVID-19 Healthcare Workers

M Campisi, L Cannella, A Bordin, P Mason, A Moretto… - 2024 - preprints.org
This study explores the role of inflammation and oxidative stress, hallmarks of COVID-19, in
accelerating cellular biological aging. We investigated early molecular markers—DNA …