Altered synaptic structure and function is a major hallmark of fragile X syndrome (FXS),
autism spectrum disorders (ASDs), and other intellectual disabilities (IDs), which are …

The human cerebellum has a protracted developmental timeline compared with the
neocortex, expanding the window of vulnerability to neurological disorders. As the …

Abstract PI3K-AKT/mTOR signaling pathway represents an essential signaling mechanism
for mammalian enzyme-related receptors in transducing signals or biological processes …

The signaling pathway of the microtubule-associated protein kinase or extracellular
regulated kinase (MAPK/ERK) is a common mechanism of extracellular information …

Next-generation sequencing (NGS) is now more accessible to clinicians and researchers.
As a result, our understanding of the genetics of neurodevelopmental disorders (NDDs) has …

Autism spectrum disorder (ASD) is characterized by deficits in sociability and
communication, and increased repetitive and/or restrictive behaviors. While the etio …

Background Sulforaphane (SF), an isothiocyanate in broccoli, has potential benefits relevant
to autism spectrum disorder (ASD) through its effects on several metabolic and immunologic …

Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with increased
prevalence and incidence in recent decades. Its etiology remains largely unclear, but it …

Abstract The Autism Spectrum Disorder (ASD) consists of a prevalent and heterogeneous
group of neurodevelopmental diseases representing a severe burden to affected individuals …

Autism spectrum disorder (ASD) is a complex neurodevelopmental monogenic disorder with
a strong genetic influence. Idiopathic autism could be defined as a type of autism that does …