The enteric nervous system is largely autonomous, and the central nervous system is
compartmentalized behind the blood-brain barrier. Yet the intestinal microbiota shapes gut …

The gastrointestinal tract is innervated by several distinct populations of neurons, whose cell
bodies either reside within (intrinsic) or outside (extrinsic) the gastrointestinal wall. Normally …

Chronic diarrhoea is a common problem, hence clear guidance on investigations is
required. This is an updated guideline from 2003 for the investigations of chronic diarrhoea …

Intestinal peristalsis is a dynamic physiologic process influenced by dietary and microbial
changes. It is tightly regulated by complex cellular interactions; however, our understanding …

For many years, a deficiency of monoamines including serotonin has been the prevailing
hypothesis on depression, yet research has failed to confirm consistent relations between …

Objective Guidelines on histopathological techniques and reporting for adult and paediatric
gastrointestinal neuromuscular pathology have been produced recently by an international …

Objectives: Chronic intestinal pseudo-obstructive (CIPO) conditions are considered the most
severe disorders of gut motility. They continue to present significant challenges in clinical …

Background Chronic intestinal pseudo‐obstruction (CIPO) represents the most severe form
of gastrointestinal dysmotility with debilitating and potentially lethal consequences …

Background & Aims The concept of enteric glia as regulators of intestinal homeostasis is
slowly gaining acceptance as a central concept in neurogastroenterology. Yet how glia …

Functional gastrointestinal disorders range from highly prevalent, but generally benign
conditions, eg, functional dyspepsia and irritable bowel syndrome, to rare and potentially life …