Ruminococcus gnavus: friend or foe for human health

EH Crost, E Coletto, A Bell… - FEMS microbiology …, 2023 - academic.oup.com
Ruminococcus gnavus was first identified in 1974 as a strict anaerobe in the gut of healthy
individuals, and for several decades, its study has been limited to specific enzymes or …

Probiotics and prebiotics in intestinal health and disease: from biology to the clinic

ME Sanders, DJ Merenstein, G Reid… - Nature reviews …, 2019 - nature.com
Probiotics and prebiotics are microbiota-management tools for improving host health. They
target gastrointestinal effects via the gut, although direct application to other sites such as …

The role of Enterobacteriaceae in gut microbiota dysbiosis in inflammatory bowel diseases

V Baldelli, F Scaldaferri, L Putignani, F Del Chierico - Microorganisms, 2021 - mdpi.com
Inflammatory bowel diseases (IBDs) are a group of chronic gastrointestinal inflammatory
diseases with unknown etiology. There is a combination of well documented factors in their …

Grape seed proanthocyanidin extract ameliorates dextran sulfate sodium-induced colitis through intestinal barrier improvement, oxidative stress reduction, and …

K Sheng, G Zhang, M Sun, S He, X Kong, J Wang… - Food & function, 2020 - pubs.rsc.org
It is widely believed that grape seed proanthocyanidin extract (GSPE) exerts antioxidant and
anti-inflammatory effects. Dietary supplementation with GSPE has been reported to alleviate …

Microbiota and mucosal defense in IBD: an update

EF Stange, BO Schroeder - Expert review of gastroenterology & …, 2019 - Taylor & Francis
Introduction: Inflammatory bowel diseases (IBD) are on the rise worldwide. This review
covers the current concepts of the etiology of Crohn´ s disease and ulcerative colitis by …

The effect of various doses of oral vitamin D3 supplementation on gut microbiota in healthy adults: a randomized, double-blinded, dose-response study

N Charoenngam, A Shirvani, TA Kalajian… - Anticancer …, 2020 - ar.iiarjournals.org
Background/Aim: To investigate the effects of vitamin D3 supplementation on gut microbiota.
Patients and Methods: Twenty adults with vitamin D insufficiency/deficiency [25 (OH) D< 30 …

Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut

A Bell, J Brunt, E Crost, L Vaux, R Nepravishta… - Nature …, 2019 - nature.com
Sialic acid (N-acetylneuraminic acid (Neu5Ac)) is commonly found in the terminal location of
colonic mucin glycans where it is a much-coveted nutrient for gut bacteria, including …

Increased abundance of proteobacteria in aggressive Crohn's disease seven years after diagnosis

MK Vester-Andersen, HC Mirsepasi-Lauridsen… - Scientific reports, 2019 - nature.com
Intestinal dysbiosis in inflammatory bowel disease (IBD) patients depend on disease activity.
We aimed to characterize the microbiota after 7 years of follow-up in an unselected cohort of …

16S rRNA and metagenomic shotgun sequencing data revealed consistent patterns of gut microbiome signature in pediatric ulcerative colitis

W Zuo, B Wang, X Bai, Y Luan, Y Fan, S Michail… - Scientific Reports, 2022 - nature.com
Dysbiosis of human gut microbiota has been reported in association with ulcerative colitis
(UC) in both children and adults using either 16S rRNA gene or shotgun sequencing data …

[HTML][HTML] Ulcerative colitis: Gut microbiota, immunopathogenesis and application of natural products in animal models

RP do Nascimento, AP da Fonseca Machado, J Galvez… - Life sciences, 2020 - Elsevier
Ulcerative colitis (UC) is an inflammatory bowel disease with increasing incidence in the
world, especially in developing countries. Although knowledge of its pathogenesis has …