Phenolic compounds versus SARS-CoV-2: An update on the main findings against COVID-19

VA Tirado-Kulieva, E Hernández-Martínez… - Heliyon, 2022 - cell.com
The COVID-19 pandemic caused by SARS-CoV-2 remains an international concern.
Although there are drugs to fight it, new natural alternatives such as polyphenols are …

Commercially available flavonols are better SARS-CoV-2 inhibitors than isoflavone and flavones

OA Chaves, N Fintelman-Rodrigues, X Wang… - Viruses, 2022 - mdpi.com
Despite the fast development of vaccines, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) is still circulating and generating variants of concern (VoC) that escape the …

Survey on Recommender Systems for Biomedical Items in Life and Health Sciences

M Pato, M Barros, FM Couto - ACM Computing Surveys, 2024 - dl.acm.org
The generation of biomedical data is of such magnitude that its retrieval and analysis have
posed several challenges. A survey of recommender system (RS) approaches in biomedical …

Chemical Composition of Honeysuckle (Lonicerae japonicae) Extracts and Their Potential in Inhibiting the SARS-CoV-2 Spike Protein and ACE2 Binding …

B Gao, L Zhu, Z Liu, Y Li, X He, X Wu… - Journal of Agricultural …, 2023 - ACS Publications
Honeysuckle (Lonicerae japonicae) has been used in functional tea products. The chemical
compositions of the water and ethanol extracts of honeysuckle were examined in the present …

Licochalcone A protects against LPS‐induced inflammation and acute lung injury by directly binding with myeloid differentiation factor 2 (MD2)

W Zhu, M Wang, L Jin, B Yang, B Bai… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose Acute lung injury (ALI)/acute respiratory distress syndrome
(ARDS) is a challenging clinical syndrome that leads to various respiratory sequelae and …

Endophytic Fungi Isolated from Ageratina adenophora Exhibits Potential Antimicrobial Activity against Multidrug-Resistant Staphylococcus aureus

J Wen, SK Okyere, J Wang, R Huang, Y Wang, L Liu… - Plants, 2023 - mdpi.com
Multidrug-resistant bacteria such as Staphylococcus aureus (MRSA) cause infections that
are difficult to treat globally, even with current available antibiotics. Therefore, there is an …

Zirconium-based metal–organic frameworks as acriflavine cargos in the battle against Coronaviruses─ A theoretical and experimental approach

PJ Jodłowski, K Dymek, G Kurowski… - … Applied Materials & …, 2022 - ACS Publications
In this study, we present a complementary approach for obtaining an effective drug, based
on acriflavine (ACF) and zirconium-based metal–organic frameworks (MOFs), against SARS …

Emden: A novel method integrating graph and transformer representations for predicting the effect of mutations on clinical drug response

Z Liu, Y Bao, W Wang, L Pan, H Wang… - Computers in Biology and …, 2023 - Elsevier
Precision medicine based on personalized genomics provides promising strategies to
enhance the efficacy of molecular-targeted therapies. However, the clinical effectiveness of …

Antiviral Flavonoids: A Natural Scaffold with Prospects as Phytomedicines against SARS-CoV2

C Saha, R Naskar, S Chakraborty - Mini Reviews in Medicinal …, 2024 - ingentaconnect.com
Flavonoids are vital candidates to fight against a wide range of pathogenic microbial
infections. Due to their therapeutic potential, many flavonoids from the herbs of traditional …

Plant‐derived flavonoids are a potential source of drugs for the treatment of liver fibrosis

B Zhao, K Liu, X Liu, Q Li, Z Li, J Xi… - Phytotherapy …, 2024 - Wiley Online Library
Liver fibrosis is a dynamic pathological process that can be triggered by any chronic liver
injury. If left unaddressed, it will inevitably progress to the severe outcomes of liver cirrhosis …