Ischaemic strokes have traditionally been classified according to the TOAST criteria, in
which strokes with unclear aetiology are classified as cryptogenic strokes. However, the …

Stroke is a threatening cerebrovascular disease caused by thrombus with high morbidity
and mortality rates. Neutrophils are the first to be recruited in the brain after stroke, which …

Background Previous studies investigated the potential mechanism of embolic stroke of
undetermined source (ESUS) from extracranial artery plaque, but there has been no study …

Background Initial studies investigating correlations between stroke etiology and clot
composition are conflicting and do not account for clot size as determined by area …

Coronavirus disease 2019 (COVID-19) is associated with a severe inflammatory response.
Inflammation affects atherosclerotic plaque vulnerability and promotes a thrombogenic …

Background: The nectin cell adhesion molecule 2 (NECTIN2) protein is a cell adhesion
molecule involved in lipid metabolism. We aimed to explore the potential role of NECTIN2 in …

Objective To determine the characteristics of intracranial plaque proximal to large vessel
occlusion (LVO) in stroke patients without major-risk cardioembolic source using 3.0 T high …

Background and purpose Hierarchical clustering, a common 'unsupervised'machine‐
learning algorithm, is advantageous for exploring potential underlying aetiology in …

Carotid atherosclerotic disease continues to be an important cause of stroke, often disabling
or fatal. Such strokes could be largely prevented through optimal medical therapy and …

Activating transcription factor 3 (ATF3) is one of the most important transcription factors that
respond to and exert dual effects on inflammatory responses. Recently, the involvement of …