[HTML][HTML] Neddylation activated TRIM25 desensitizes triple-negative breast cancer to paclitaxel via TFEB-mediated autophagy

B Zheng, F Qian, X Wang, Y Wang, B Zhou… - Journal of Experimental & …, 2024 - Springer
Background Paclitaxel (PTX) treatment resistance is an important factor leading to poor
prognosis in triple-negative breast cancer (TNBC), therefore there is an urgent need to …

[HTML][HTML] TRIM6 promotes glioma malignant progression by enhancing FOXO3A ubiquitination and degradation

J Guo, J Wang, P Zhang, P Wen, S Zhang, X Dong… - Translational …, 2024 - Elsevier
Purpose TRIM6, an E3 ubiquitin ligase with tripartite motif, directly targets protein substrates
for degradation through ubiquitination. Studies have shown that TRIM6 plays a significant …