Drugs with poor biopharmaceutical performance are the main obstacle to the development
and design of medicinal preparations. The anisotropic surface chemistry of different surfaces …

Based on the recent observation that the antiplatelet agent ticagrelor and one of its
metabolite exert bactericidal activity against gram-positive bacteria, a series of 1, 2, 3 …

Targeting the polyamine biosynthetic pathway by inhibiting ornithine decarboxylase (ODC)
is a powerful approach in the fight against diverse viruses, including SARS-CoV-2 …

The study presents the design, synthesis, and characterization of DCNP-2TPA, a novel “hot
exciton” fluorophore featuring a donor-acceptor structure combining dicyanophenanthrene …

The title compound, N-benzoyl-2′-hydroxy-3-methylisovaline, representing synthon
polymorphism, can be interesting inter alia from the point of view of modern supramolecular …

This work is the first, according to our knowledge, complete structural report on the solid-
state supramolecular architecture of antidiabetic drug repaglinide. Here, we present a series …

Solventless cyclocondensation of 2-aminothiophenol with thiourea afforded the benzo [d]
oxazole-2-thiol (3a) capable of existing also in the tautomeric form benzo [d] oxazole-2 (3H) …

Here, we report the synthesis, X-ray crystallography, DFT calculation, and ADME prediction
of some new isoxazole-based flexible analogs. The key acetimidamide intermediates (1) …

Closo m-C2B10H12 can perform as a novel core of globular periphery-decorated
macromolecules. To do this, a new class of di and tetrabranched m-carborane derivatives …

In this work, we optimized XH··· C20 (X= F, Cl, Br) systems at the LC-ωPBE/6-311G (d, p)
level of theory and illustrated structural, electronic and vibrational properties in these …