The interferon (IFN) response is the major early innate immune response against invading
viral pathogens and is even capable of mediating sterilizing antiviral immunity without the …

Background: The COVID-19 period highlights a huge problem that has been developing for
decades, the control of science by industry. In the 1950s, the tobacco industry set the …

Children generally develop a mild disease after SARS-CoV-2 infection whereas older adults
are at risk of developing severe COVID-19. Recent transcriptomic analysis showed pre …

Hyper-transmissibility with decreased disease severity is a typical characteristic of the SARS-
CoV-2 Omicron variant. To understand this phenomenon, we used various bioinformatics …

Background The role of type I interferons (IFNs) in the early phase of COVID-19 remains
unclear. Objectives To evaluate the relationship between IFN-I levels in patients with COVID …

Background. Interferon is a marker of host antiviral immunity, which is disordered in COVID-
19 patients. ERV can affect the secretion of interferon through the cGAS-STING pathway. In …

Autoantibodies (AABs) neutralizing type I interferons (IFN) underlie about 15% of cases of
critical coronavirus disease 2019 (COVID-19) pneumonia. The impact of autoimmunity …

Background Immune response indicators in the early phase of COVID-19, including
interferon and neutralizing responses against SARS-CoV-2, which predict hypoxemia …

Contradictory results have been reported regarding interferon (IFN) lambda (λ1–3) and IFN
gamma (γ) production in COVID-19 patients. To gain insight into the roles played by these …

Respiratory viral infections frequently lead to severe respiratory disease, particularly in
vulnerable populations such as young children, individuals with chronic lung conditions and …