Therapeutic role of neutralizing antibody for the treatment against SARS-CoV-2 and its emerging variants: A clinical and pre-clinical perspective
Since early 2020, the entire world has been facing a disastrous outbreak of the SARS-CoV-2
virus, with massive reporting of death and infections per day. Medical practitioners adopted …
virus, with massive reporting of death and infections per day. Medical practitioners adopted …
Review of therapeutic mechanisms and applications based on SARS-CoV-2 neutralizing antibodies
COVID-19 pandemic is a global public health emergency. Despite extensive research, there
are still few effective treatment options available today. Neutralizing-antibody-based …
are still few effective treatment options available today. Neutralizing-antibody-based …
Plant virus‐derived nanoparticles decorated with genetically encoded SARS‐CoV‐2 nanobodies display enhanced neutralizing activity
F Merwaiss, E Lozano‐Sanchez… - Plant Biotechnology …, 2024 - Wiley Online Library
Viral nanoparticles (VNPs) are a new class of virus‐based formulations that can be used as
building blocks to implement a variety of functions of potential interest in biotechnology and …
building blocks to implement a variety of functions of potential interest in biotechnology and …
Pre-pandemic SARS-CoV-2-specific IFN-γ and antibody responses were low in Ugandan samples and significantly reduced in HIV-positive specimens
H Nantambi, J Sembera, V Ankunda, I Ssali… - Frontiers in …, 2023 - frontiersin.org
Introduction We investigated whether prior SARS-CoV-2-specific IFN-γ and antibody
responses in Ugandan COVID-19 pre-pandemic specimens aligned to this population's low …
responses in Ugandan COVID-19 pre-pandemic specimens aligned to this population's low …
SARS‐CoV‐2 neutralising antibody therapies: Recent advances and future challenges
The COVID‐19 pandemic represents an unparalleled global public health crisis. Despite
concerted research endeavours, the repertoire of effective treatment options remains limited …
concerted research endeavours, the repertoire of effective treatment options remains limited …
Post-vaccination SARS-CoV-2 seroprevalence in children aged 3-11 years and the positivity in unvaccinated children: a retrospective, single-center study
J Li, M Ge, S Dai, Q Song, W Liu, Y Wang… - Frontiers in …, 2022 - frontiersin.org
Objective To analyze the positivity and levels of SARS-CoV-2 antibodies in vaccinated
children to evaluate the humoral immune response of vaccination on pediatric population …
children to evaluate the humoral immune response of vaccination on pediatric population …
Inhibition of SARS-CoV-2 infection in human airway epithelium with a xeno-nucleic acid aptamer
N Razi, W Li, MA Ignacio, JM Loube, EL Agostino… - Respiratory …, 2023 - Springer
Abstract Background SARS-CoV-2, the agent responsible for the COVID-19 pandemic,
enters cells through viral spike glycoprotein binding to the cellular receptor, angiotensin …
enters cells through viral spike glycoprotein binding to the cellular receptor, angiotensin …
Spotlight on contributory role of host immunogenetic profiling in SARS-CoV-2 infection: Susceptibility, severity, mortality, and vaccine effectiveness
S Yazdanparast, M Bakhtiyaridovvombaygi, F Mikanik… - Life Sciences, 2023 - Elsevier
Abstract Background The SARS-CoV-2 virus has spread continuously worldwide,
characterized by various clinical symptoms. The immune system responds to SARS-CoV-2 …
characterized by various clinical symptoms. The immune system responds to SARS-CoV-2 …
IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern
MR Chang, L Tomasovic, NA Kuzmina, AJ Ronk… - Nature …, 2022 - nature.com
Monoclonal antibodies are a promising approach to treat COVID-19, however the
emergence of SARS-CoV-2 variants has challenged the efficacy and future of these …
emergence of SARS-CoV-2 variants has challenged the efficacy and future of these …
Interaction between spike protein of SARS-CoV-2 and human virus receptor ACE2 using two-color fluorescence cross-correlation spectroscopy
A Fujimoto, Y Lyu, M Kinjo, A Kitamura - Applied Sciences, 2021 - mdpi.com
Infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the cause of
coronavirus disease 2019 (COVID-19), is initiated by the interaction between a receptor …
coronavirus disease 2019 (COVID-19), is initiated by the interaction between a receptor …