Glioblastoma (GBM) is an aggressive and lethal disease that often results in a poor
prognosis. Unlike most solid tumors, GBM is characterized by diffuse infiltrating margins …

Nitric oxide has been implicated in biology and progression of glioblastoma (GBM) being
able to influence the cellular signal depending on the concentration and duration of cell …

Simple Summary In this manuscript, we review the most relevant biological findings on
glioblastoma peritumoral tissue. This area, which is beyond frank tumoral tissue, presents a …

Tumor-initiating cells contained within the aggressive brain tumor glioma (glioma stem cells,
GSCs) promote radioresistance and disease recurrence. However, mechanisms of …

Glioblastomas (GBMs) are the most common primary brain tumors with poor prognosis due
to their aggressive growth accompanied by invasive behavior and therapy-resistance. These …

Cellular quiescence is a reversible, non-cycling state controlled by epigenetic,
transcriptional and niche-associated molecular factors. Quiescence is a condition where …

Glioblastoma multiforme (GBM) is a primary brain tumor that is very aggressive, resistant to
treatment, and characterized by a high degree of anaplasia and proliferation. Routine …

In glioblastoma, a fraction of malignant cells consists of therapy-resistant glioblastoma stem
cells (GSCs) residing in protective niches that recapitulate hematopoietic stem cell (HSC) …

Background Several studies have examined the impact of anesthetics on cancer recurrence.
Isoflurane but not desflurane has protumoral effects. We hypothesize the use of isoflurane …

Simple Summary Glioblastoma stem-like cells (GSCs) are responsible for most of the
malignant characteristics of glioblastoma, including therapeutic resistance, tumour …