The development of potent and selective therapeutic approaches to glioblastoma (GBM)
requires the identification of molecular pathways that critically regulate the survival and …

Glioblastoma (GBM) is a common primary brain malignancy known for its ability to invade
the brain, resistance to chemotherapy and radiotherapy, tendency to recur frequently, and …

Glioblastoma multiforme (GBM) is the most deadly form of brain cancer. Recurrence is
common, and established therapies have not been able to significantly extend overall …

Glioblastoma is the most common and malignant form of brain cancer, for which the
standard treatment is maximal surgical resection, radiotherapy and chemotherapy. Despite …

The modulation of tumor growth and development in vitro has always been one of the key
factors in the research of the malignant transformation, including gliomas, prevalent and …

The management of glioblastomas (GBMs) is challenged by the development of therapeutic
resistance and early disease recurrence, despite multi-modal therapy. This may be …

Aims: Assess the impact of radiation doses to neural stem cell (NSC) niches in patients with
IDH-wild-type glioblastoma. Materials and Methods: Fifty patients were included in the study …

Malignant gliomas are one of the most common and lethal brain tumors with poor prognosis.
Most patients with glioblastoma (GBM) die within 2 years of diagnosis, even after receiving …

Cancer stem cells (CSCs) are a heterogeneous and dynamic self‐renewing population that
stands at the top of tumor cellular hierarchy and contribute to tumor recurrence and …

Glioblastoma (GBM) is an extremely aggressive and incurable primary brain tumor with a 10-
year survival of just 0.71%. Cancer stem cells (CSCs) are thought to seed GBM's inevitable …