[HTML][HTML] Drug development and use in the elderly: search for the right dose and dosing regimen

RR Shah - British journal of clinical pharmacology, 2004 - ncbi.nlm.nih.gov
Across the globe over the last few decades, there has been a remarkable increase in the
proportion of the population which is elderly, and this trend is set to continue. Data from 10 …

Dose of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers and outcomes in heart failure: a meta-analysis

MS Khan, GC Fonarow, A Ahmed… - Circulation: Heart …, 2017 - Am Heart Assoc
Background The association between angiotensin-converting enzyme inhibitors (ACEI) and
angiotensin receptor blockers (ARB) doses on outcomes in patients with heart failure (HF) …

Lack of improvement of clinical outcomes by a low-cost, hospital-based heart failure management programme

G Nucifora, MC Albanese, P De Biaggio… - Journal of …, 2006 - journals.lww.com
Objective Heart failure (HF) is a major health problem resulting in a high financial burden for
the healthcare system. Many previous HF management programmes reduced adverse …

Role and optimal dosing of angiotensin-converting enzyme inhibitors in heart failure

D Kazi, A Deswal - Cardiology clinics, 2008 - Elsevier
Based on overwhelming data demonstrating reduced morbidity and mortality, ACE inhibitors
form a mainstay of therapy in all patients with symptomatic left ventricular systolic …

Angiotensin-converting enzyme inhibitors

DA Sica, TWB Gehr - Hypertension. Philadelphia: Elsevier …, 2005 - api.taylorfrancis.com
SUMMARY ACE inhibitors have enjoyed a lengthy history of use. The first application of
ACE inhibitors was in the treatment of hypertension where they were shown to reduce blood …

[HTML][HTML] Relationship between beta-blocker and angiotensin-converting enzyme inhibitor dose and clinical outcome following acute myocardial infarction

S Grall, L Biere, M Le Nezet, JM Bouvier… - Circulation …, 2015 - jstage.jst.go.jp
Background: Benefit of β-blockers (BB) and angiotensin-converting-enzyme inhibitors
(ACEI) on mortality following acute myocardial infarction (MI) is well demonstrated. This …

[HTML][HTML] Potential benefits of Chinese Herbal Medicine for elderly patients with cardiovascular diseases

J Luo, H Xu, KJ Chen - Journal of Geriatric Cardiology: JGC, 2013 - ncbi.nlm.nih.gov
Abstract Chinese Herbal Medicine (CHM), as the most common form of traditional Chinese
medicine (TCM), has been playing an important role in the treatment of elderly …

[HTML][HTML] Dose response of ACE inhibitors: implications of the SECURE trial

E Lonn - Trials, 2001 - Springer
The choice of the appropriate dosage of ACE inhibitor in clinical practice is an important
one. The available evidence suggests that in chronic heart failure as well as in chronic …

Structure and markers of appropriateness, quality and performance of drug treatment over a 1-year period after hospital discharge in a cohort of elderly patients with …

S Harder, P Fischer, M Krause-Schäfer… - European journal of …, 2005 - Springer
In a group of elderly patients over 65 years of age with at least two cardiovascular diagnoses
requiring chronic medication (n= 424), drug therapy at hospital discharge and at home …

Outcomes and the quality of care for patients hospitalized with heart failure

JC Luthi, WD Flanders, SR Pitts… - … Journal for Quality in …, 2004 - academic.oup.com
Objective. The purpose of this study was to determine whether process quality indicators
derived from evidence-based guidelines for heart failure patients were associated with …