Estrogen actions are largely dependent on the intracellular estrogen receptor (ER) levels.
During aging the decline of estrogens or ER leads to a loss in antiinflammatory protection …

A common biochemical characteristic of aging is proteotoxicity ie the accumulation of altered
proteins. While many studies have shown that NAD+ is important when lifespan is …

Contrast‐induced nephropathy (CIN) often occurs after contrast media‐related procedures
and is associated with increased morbidity and mortality. The acute renal failure observed …

Diabetes mellitus (DM) and chronic kidney disease (CKD) are common in middle aged and
elderly individuals. DM may accelerate the aging process, and the age-related declines in …

Background Diabetic patients on peritoneal dialysis (PD) have lower survival and are more
likely complicated with inflammation than their non-diabetic counterparts. Here, we explored …

Background: Therapeutic fasting improves joint pain in patients with osteoarthritis (OA), but
the underlying mechanisms are unknown. Interactions of advanced glycation end products …

Chronic kidney disease (CKD) is a clinical condition that can end in endstage renal disease
(ESRD) and needs dialysis or a kidney transplant. Hypertension, diabetes, obesity, and …

Alors qu'elle lutte contre l'arthrite/arthrose qui la fait souffrir sévèrement et la prive presque
entièrement de l'usage de ses doigts, Jacqueline Lagacé découvre le régime hypotoxique …

Trait enhanced soybean oils are valued for their improvements in functionality, enrichment in
healthful and sustainable long chain omega 3 fatty acids or for their enrichment in oleic acid …

The desire to extend lifespan and health has occupied the scientific and lay communities
during most of recorded history. This quest includes the search for some magical elixir …