Background. Better therapeutic drugs are required for treating hypertensive diabetic
nephropathy. In our previous study, the Huaju Xiaoji (HJXJ) formula promoted the renal …

Background: In chronic kidney disease (CKD), the accumulation of advanced oxidation
protein products (AOPPs) is prevalent. Hypertrophy and epithelial-to-mesenchymal …

Camellia seed oil (CO) is used as edible oil in southern China because of its excellent fatty
acid composition and abundant bioactive compounds. Chronic kidney disease (CKD) is one …

Renal ischemia-reperfusion (I/R) injury ranks as the primary cause of acute renal injury with
severe morbidity and mortality. Side population (SP) cells have recently drawn increasing …

Endoplasmic reticulum stress (ERS) plays a crucial role in the pathogenesis of diabetic
nephropathy (DN), and it is often accompanied by an increase in reactive oxygen species …

Angiotensin II (AngII) plays an important role in the pathogenesis of hypertension and
associated renal injuries. To elucidate the molecular mechanism by which AngII induces …

CCAAT/enhancer‐binding homologous protein (CHOP), a transcriptional regulator induced
by endoplasmic reticulum stress (ER stress) is a pivotal factor in the ER stress‐mediated …

Various factors, both internal and external, can disrupt endoplasmic reticulum (ER)
homeostasis and increase the burden of protein folding, resulting in ER stress. While short …

Previous studies, by this group and others, have shown that vasoactive intestinal peptide
(VIP) stimulates aldosterone secretion, and that the actions of VIP on aldosterone secretion …

We investigated pregnancy-associated plasma protein-A (PAPP-A) in diabetic nephropathy.
Normal human kidney showed specific staining for PAPP-A in glomeruli, and this staining …