[HTML][HTML] Research trend of epigenetics and depression: adolescents' research needs to strengthen

D Yuan, Y Meng, Z Ai, S Zhou - Frontiers in Neuroscience, 2024 - frontiersin.org
Objective With its high prevalence, depression's pathogenesis remains unclear. Recent
attention has turned to the interplay between depression and epigenetic modifications …

[HTML][HTML] Probing the genomic landscape of human sexuality: a critical systematic review of the literature

NL Bragazzi, M Converti, A Crapanzano… - Frontiers in …, 2023 - frontiersin.org
Whether human sexuality is the result of nature or nurture (or their complex interplay)
represents a hot, often ideologically driven, and highly polarized debate with political and …

[HTML][HTML] Correlation between variants of the CREB1 and GRM7 genes and risk of depression

L Wang, X Tang, P Liang, C Zhou, Y Sun, Y Liang - BMC psychiatry, 2023 - Springer
The pathogenesis of depression involves cAMP-response element binding protein1
(CREB1) and metabotropic glutamate receptor 7 (GRM7), and their genetic polymorphisms …

OXTR moderates adverse childhood experiences on depressive symptoms among incarcerated males

J Zhang, C Yang, J Leng, J Liu, P Gong… - Journal of Psychiatric …, 2021 - Elsevier
Objectives This study examined the moderation of an oxytocin receptor (OXTR) gene in the
link between childhood adversity and depressive symptoms among incarcerated males …

To what extent do social support and coping strategies mediate the relation between childhood maltreatment and major depressive disorder: A longitudinal community …

M Li, KJ O'Donnell, J Caron, MJ Meaney… - Development and …, 2024 - cambridge.org
This study aimed to articulate the roles of social support and coping strategies in the relation
between childhood maltreatment (CM) and subsequent major depressive disorder (MDD) …

[HTML][HTML] Impact of gene-by-trauma interaction in MDD-related multimorbidity clusters

S Bonk, N Eszlari, K Kirchner, A Gezsi, L Garvert… - Journal of affective …, 2024 - Elsevier
Background Major depressive disorder (MDD) is considerably heterogeneous in terms of
comorbidities, which may hamper the disentanglement of its biological mechanism. In a …

[HTML][HTML] Exploring the similarities between risk factors triggering depression in humans and elevated in-cage “inactive but awake” behavior in laboratory mice

O Schmitt, E Finnegan, A Trevarthen… - Frontiers in Veterinary …, 2024 - frontiersin.org
Introduction Depression is a human mental disorder that can also be inferred in non-human
animals. This study explored whether time spent inactive but awake (“IBA”) in the home …

[HTML][HTML] Default mode network alterations induced by childhood trauma correlate with emotional function and SLC6A4 expression

T Tian, J Li, G Zhang, J Wang, D Liu, C Wan… - Frontiers in …, 2022 - frontiersin.org
As one of the most studied resting-state functional networks, default mode network (DMN) is
related to pathogenesis in neuropsychiatry. However, it is unclear whether changed DMN …

[HTML][HTML] Gene-environment interactions between CREB1 and childhood maltreatment on aggression among male Chinese adolescents

Y Zhang, C Kang, H Yang, M Yang, S Wei, Y Wang… - Scientific reports, 2022 - nature.com
Both the genetic and environmental factors may affect aggression susceptibility. However,
the conclusions of these associations remain discrepant. In addition, studies that explored …

[HTML][HTML] Effects of the interaction between affective temperaments and BIS/BAS on depressive symptoms in individuals with major depressive disorder

K Toyoshima, J Masuya, M Ono, M Honyashiki… - International journal of …, 2022 - mdpi.com
Depressive symptoms (DepS) associated with major depressive disorder (MDD) are
influenced by affective temperaments (ATs), behavioral inhibition system (BIS), and …