[HTML][HTML] Ischemic brain edema: Emerging cellular mechanisms and therapeutic approaches

W Han, Y Song, M Rocha, Y Shi - Neurobiology of Disease, 2023 - Elsevier
Brain edema is one of the most devastating consequences of ischemic stroke. Malignant
cerebral edema is the main reason accounting for the high mortality rate of large …

Pivotal role of multiphase computed tomography angiography for collateral assessment in patients with acute ischemic stroke

G Busto, A Morotti, E Carlesi, A Fiorenza… - La radiologia …, 2023 - Springer
The cerebral collateral circulation is the main compensatory mechanism that maintains the
ischemic penumbra viable, the tissue at risk for infarction that can be saved if blood flow is …

Poor venous outflow profiles increase the risk of reperfusion hemorrhage after endovascular treatment

L Winkelmeier, JJ Heit, G Adusumilli… - Journal of Cerebral …, 2023 - journals.sagepub.com
To investigate whether unfavorable cerebral venous outflow (VO) predicts reperfusion
hemorrhage after endovascular treatment (EVT), we conducted a retrospective multicenter …

Microvascular dysfunction associated with unfavorable venous outflow in acute ischemic stroke patients

X Li, L Lin, J Zhang, Y Fan, S Xing… - Journal of Cerebral …, 2023 - journals.sagepub.com
Unfavorable venous outflow (VO) is associated with cerebral edema, which represents
microvascular dysfunction. This study estimated the relationship between VO and …

Synchronous superficial middle cerebral vein outflow correlates favorable tissue fate after mechanical thrombectomy for acute ischemic stroke

L Dai, Z Sun, J Jiang, J Wei, X Song, S Chen, Y Li - Academic Radiology, 2024 - Elsevier
Rationale and Objectives The purpose of this study was to determine the association
between hemispheric synchrony in venous outflow at baseline and tissue fate after …

Early edema within the ischemic core is time-dependent and associated with functional outcomes of acute ischemic stroke patients

Q Han, J Yang, X Gao, J Li, Y Wu, Y Xu… - Frontiers in …, 2022 - frontiersin.org
Objective To investigate the difference in early edema, quantified by net water uptake (NWU)
based on computed tomography (CT) between ischemic core and penumbra and to explore …

Association between occlusion location, net water uptake and ischemic lesion growth in large vessel anterior circulation strokes

L Winkelmeier, JJ Heit, G Broocks… - Journal of Cerebral …, 2024 - journals.sagepub.com
Ischemic lesion net water uptake (NWU) represents a quantitative imaging biomarker for
cerebral edema in acute ischemic stroke. Data on NWU for distinct occlusion locations …

Prolonged venous transit on perfusion imaging is associated with higher odds of mortality in successfully reperfused patients with large vessel occlusion stroke

VS Yedavalli, M Koneru, M Hoseinyazdi… - Journal of …, 2024 - jnis.bmj.com
Background Poor venous outflow (VO) profiles are associated with unfavorable outcomes in
patients with acute ischemic stroke caused by large vessel occlusion (AIS-LVO), despite …

[HTML][HTML] Venous outflow profiles are linked to clinical outcomes in ischemic stroke patients with extensive baseline infarct

L Winkelmeier, G Broocks, H Kniep, V Geest… - Journal of …, 2022 - synapse.koreamed.org
Background and Purpose The benefit of endovascular thrombectomy (EVT) treatment is still
unclear in stroke patients presenting with extensive baseline infarct. The use of additional …

Brain edema growth after thrombectomy is associated with comprehensive collateral blood flow

TD Faizy, L Winkelmeier, M Mlynash… - Journal of …, 2023 - jnis.bmj.com
Background We determined whether a comprehensive assessment of cerebral collateral
blood flow is associated with ischemic lesion edema growth in patients successfully treated …