[HTML][HTML] Mapping the genetic architecture of cortical morphology through neuroimaging: progress and perspectives

D van der Meer, T Kaufmann - Translational Psychiatry, 2022 - nature.com
Cortical morphology is a key determinant of cognitive ability and mental health. Its
development is a highly intricate process spanning decades, involving the coordinated …

The enhancing NeuroImaging genetics through meta‐analysis consortium: 10 Years of global collaborations in human brain mapping

PM Thompson, N Jahanshad, L Schmaal… - Human brain …, 2022 - Wiley Online Library
Abstract This Special Issue of Human Brain Mapping is dedicated to a 10‐year anniversary
of the Enhancing NeuroImaging Genetics through Meta‐Analysis (ENIGMA) Consortium. It …

New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications

OA Andreassen, GFL Hindley, O Frei… - World …, 2023 - Wiley Online Library
Psychiatric genetics has made substantial progress in the last decade, providing new
insights into the genetic etiology of psychiatric disorders, and paving the way for precision …

Improving power in functional magnetic resonance imaging by moving beyond cluster-level inference

S Noble, AF Mejia, A Zalesky… - Proceedings of the …, 2022 - National Acad Sciences
Inference in neuroimaging typically occurs at the level of focal brain areas or circuits. Yet,
increasingly, well-powered studies paint a much richer picture of broad-scale effects …

[HTML][HTML] Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology

AA Shadrin, T Kaufmann, D van der Meer, CE Palmer… - Neuroimage, 2021 - Elsevier
Brain morphology has been shown to be highly heritable, yet only a small portion of the
heritability is explained by the genetic variants discovered so far. Here we extended the …

Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy

G Hindley, AA Shadrin, D van der Meer… - Nature human …, 2023 - nature.com
Personality and cognitive function are heritable mental traits whose genetic foundations may
be distributed across interconnected brain functions. Previous studies have typically treated …

The genetic architecture of human cortical folding

D Van Der Meer, T Kaufmann, AA Shadrin… - Science …, 2021 - science.org
The folding of the human cerebral cortex is a highly genetically regulated process that
allows for a much larger surface area to fit into the cranial vault and optimizes functional …

Genomic loci influence patterns of structural covariance in the human brain

J Wen, IM Nasrallah, A Abdulkadir… - Proceedings of the …, 2023 - National Acad Sciences
Normal and pathologic neurobiological processes influence brain morphology in
coordinated ways that give rise to patterns of structural covariance (PSC) across brain …

Genetic architecture of the white matter connectome of the human brain

Z Sha, D Schijven, SE Fisher, C Francks - Science advances, 2023 - science.org
White matter tracts form the structural basis of large-scale brain networks. We applied brain-
wide tractography to diffusion images from 30,810 adults (UK Biobank) and found significant …

[HTML][HTML] Genome-wide association study of Alzheimer's disease brain imaging biomarkers and neuropsychological phenotypes in the European medical information …

J Homann, T Osburg, O Ohlei, V Dobricic… - Frontiers in aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is the most frequent neurodegenerative disease with an
increasing prevalence in industrialized, ageing populations. AD susceptibility has an …