[HTML][HTML] Adipose tissue inflammation and pulmonary dysfunction in obesity

G Palma, GP Sorice, VA Genchi, F Giordano… - International Journal of …, 2022 - mdpi.com
Obesity is a chronic disease caused by an excess of adipose tissue that may impair health
by altering the functionality of various organs, including the lungs. Excessive deposition of …

SARS-CoV-2 infection and its effects on the endocrine system

C Steenblock, N Toepfner, F Beuschlein… - Best practice & research …, 2023 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing corona virus
disease 2019 (COVID-19) can infect multiple tissues, including endocrine organs, such as …

[HTML][HTML] SARS-CoV-2 infects adipose tissue in a fat depot-and viral lineage-dependent manner

TD Saccon, F Mousovich-Neto, RG Ludwig… - Nature …, 2022 - nature.com
Visceral adiposity is a risk factor for severe COVID-19, and a link between adipose tissue
infection and disease progression has been proposed. Here we demonstrate that SARS …

[HTML][HTML] Obesity and COVID-19: What are the Consequences?

C Steenblock, M Hassanein, EG Khan… - Hormone and …, 2022 - thieme-connect.com
Obesity is an increasing health problem all over the world. In combination with the current
COVID-19 pandemic, this has turned into a massive challenge as individuals with …

[HTML][HTML] Mechanisms and pathophysiology of SARS-CoV-2 infection of the adipose tissue

J Moser, M Emous, P Heeringa… - Trends in Endocrinology …, 2023 - cell.com
Obesity is an independent risk factor for severe COVID-19, yet there remains a lack of
consensus on the mechanisms underlying this relationship. A hypothesis that has garnered …

[HTML][HTML] Beyond energy balance regulation: The underestimated role of adipose tissues in host defense against pathogens

J Barthelemy, G Bogard, I Wolowczuk - Frontiers in Immunology, 2023 - frontiersin.org
Although the adipose tissue (AT) is a central metabolic organ in the regulation of whole-
body energy homeostasis, it is also an important endocrine and immunological organ. As an …

[HTML][HTML] Fatal COVID-19 pulmonary disease involves ferroptosis

B Qiu, F Zandkarimi, A Saqi, C Castagna, H Tan… - Nature …, 2024 - nature.com
SARS-CoV-2 infection causes severe pulmonary manifestations, with poorly understood
mechanisms and limited treatment options. Hyperferritinemia and disrupted lung iron …

Do adipocytes serve as a reservoir for severe acute respiratory syndrome coronavirus-2?

C Steenblock, N Bechmann… - Journal of …, 2023 - joe.bioscientifica.com
Obesity is associated with a higher risk of severe coronavirus disease 2019 (COVID-19) and
increased mortality. In the current study, we have investigated the expression of ACE2 …

[HTML][HTML] The role of obesity, body composition, and nutrition in COVID-19 pandemia: A narrative review

AP Rossi, V Muollo, Z Dalla Valle, S Urbani… - Nutrients, 2022 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic has spread worldwide, infecting
nearly 500 million people, with more than 6 million deaths recorded globally. Obesity leads …

[HTML][HTML] Knowledge, experiences, and perceptions relating to obesity management among primary care physicians in the Lazio Region, Italy

V Guglielmi, D Capoccia, B Russo… - Frontiers in …, 2023 - frontiersin.org
Background Primary care providers (PCPs) play an essential role in obesity care as they
represent the first contact for patients seeking weight loss interventions. Objective This study …