[HTML][HTML] Sex and gender differences in myocarditis and dilated cardiomyopathy: an update

DL Fairweather, DJ Beetler, N Musigk… - Frontiers in …, 2023 - frontiersin.org
In the past decade there has been a growing interest in understanding sex and gender
differences in myocarditis and dilated cardiomyopathy (DCM), and the purpose of this review …

Systematic review of sodium‐glucose cotransporter 2 inhibitors: a hopeful prospect in tackling heart failure‐related events

B Aziri, E Begic, S Jankovic, Z Mladenovic… - ESC heart …, 2023 - Wiley Online Library
In modern cardiology, sodium‐glucose cotransporter 2 (SGLT2) inhibitors are critical
components of heart failure (HF) treatment algorithms and exert their effects primarily by …

Sex differences in characteristics, outcomes, and treatment response with dapagliflozin across the range of ejection fraction in patients with heart failure: insights from …

X Wang, M Vaduganathan, BL Claggett, SM Hegde… - Circulation, 2023 - Am Heart Assoc
Background: Sodium-glucose cotransporter-2 inhibitors have emerged as a key
pharmacotherapy in heart failure (HF) with both reduced and preserved ejection fraction …

SGLT2 inhibitor therapy for transthyretin amyloid cardiomyopathy: early tolerance and clinical response to dapagliflozin

S Dobner, B Bernhard, B Asatryan… - ESC Heart …, 2023 - Wiley Online Library
Aims Sodium‐glucose cotransporter 2 inhibitors (SGLT2i) improve clinical outcomes in heart
failure patients with reduced and preserved left ventricular ejection fraction (LVEF), but have …

Cardiovascular effects of non-insulin glucose-lowering agents: a comprehensive review of trial evidence and potential cardioprotective mechanisms

G Savarese, J Butler, LH Lund, DL Bhatt… - Cardiovascular …, 2022 - academic.oup.com
Type 2 diabetes mellitus (T2DM) is highly prevalent and associated with a two-fold
increased mortality, mostly explained by cardiovascular diseases. Trial evidence on older …

Effects of empagliflozin in women and men with heart failure and preserved ejection fraction

J Butler, G Filippatos, TJ Siddiqi, JP Ferreira… - Circulation, 2022 - Am Heart Assoc
Background: Women and men with heart failure (HF) and preserved ejection fraction may
differ in their clinical characteristics and their response to therapy. The aim of this study was …

[HTML][HTML] Heart failure in type 2 diabetes: current perspectives on screening, diagnosis and management

A Ceriello, D Catrinoiu, C Chandramouli… - Cardiovascular …, 2021 - Springer
Type 2 diabetes is one of the most relevant risk factors for heart failure, the prevalence of
which is increasing worldwide. The aim of the review is to highlight the current perspectives …

Extrapolating long-term event-free and overall survival with dapagliflozin in patients with heart failure and reduced ejection fraction: an exploratory analysis of a phase …

KF Docherty, PS Jhund, B Claggett, JP Ferreira… - JAMA …, 2021 - jamanetwork.com
Importance Sodium glucose cotransporter 2 inhibitors reduce morbidity and mortality in
patients with heart failure and reduced ejection fraction (HFrEF). Clinicians may find …

[HTML][HTML] Sodium-glucose cotransporter-2 inhibitors improve heart failure with reduced ejection fraction outcomes by reducing edema and congestion

M Hernandez, RD Sullivan, ME McCune, GL Reed… - Diagnostics, 2022 - mdpi.com
Pathological sodium-water retention or edema/congestion is a primary cause of heart failure
(HF) decompensation, clinical symptoms, hospitalization, reduced quality of life, and …

[HTML][HTML] Current role of SLGT2 inhibitors in the management of the whole spectrum of heart failure: focus on dapagliflozin

C Escobar, D Pascual-Figal, L Manzano… - Journal of Clinical …, 2023 - mdpi.com
Heart failure (HF) is associated with a high morbidity and mortality burden. In light of more
recent evidence, SGLT2 inhibitors are currently recommended as first-line therapy in …