Chronic obstructive pulmonary disease (COPD) is a debilitating heterogeneous disease
characterised by unregulated proteolytic destruction of lung tissue mediated via a protease …

Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible
fibrotic disease associated with respiratory failure. The disease remains idiopathic, but …

Rationale: Since their approval, there has been no real-world or randomized trial evidence
evaluating the effect of the antifibrotic medications pirfenidone and nintedanib on clinically …

Idiopathic pulmonary fibrosis (IPF) is a progressive disease thought to result from impaired
lung repair following injury and is strongly associated with aging. While vascular alterations …

Sufficient epidemiological investigations demonstrate that there is a close correlation
between obesity and vascular dysfunction. Nevertheless, specific mechanisms underlying …

The chronic progressive decline in lung function observed in idiopathic pulmonary fibrosis
(IPF) appears to result from persistent nonresolving injury to the epithelium, impaired …

The wingless (Wnt) family of signaling ligands contributes significantly to lung development
and is highly expressed in patients with usual interstitial pneumonia (UIP). We sought to …

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterized by an
exacerbated fibrotic response. Although molecular and cellular determinants involved in the …

Idiopathic pulmonary fibrosis is characterized by a progressive scarring and stiffening of the
peripheral lung tissue that decreases lung function. Over the course of the disease, the lung …

Idiopathic pulmonary fibrosis (IPF) is an example of interstitial lung diseases that is
characterized by chronic, progressive, and fibrotic lung injuries. During lung fibrosis, normal …