COVID-19, which is caused by the SARS-CoV-2, has ravaged the world for the past 2 years.
Here, we review the current state of research into the disease with focus on its history …

Background: From the start of the COVID-19 pandemic, new SARS-CoV-2 variants have
emerged that potentially affect transmissibility, severity, and immune evasion in infected …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is rarely fatal in
children and young people (CYP,< 18 years old), but quantifying the risk of death is …

Introduction Loss-of-function TLR7 variants have been recently reported in a small number
of males to underlie strong predisposition to severe COVID-19. We aimed to determine the …

Background It is important to predict which patients infected by SARS-CoV-2 are at higher
risk of life-threatening COVID-19. Several studies suggest that neutralizing auto-antibodies …

Abstract The Delta (B. 1.617. 2) variant was the predominant UK circulating SARS-CoV-2
strain between May and December 2021. How Delta infection compares with previous …

Background: The Delta (B. 1.617. 2) SARS-CoV-2 variant was the predominant UK
circulating strain between May and November 2021. We investigated whether COVID-19 …

Background Infection by the SARS-Cov-2 virus produces in humans a disease of highly
variable and unpredictable severity. The presence of frequent genetic single nucleotide …

Although advanced age and presence of comorbidities significantly impact the variation
observed in the clinical symptoms of COVID-19, it has been suggested that genetic variants …

Background COVID-19 is associated with several risk factors such as distinct ethnicities
(genetic ancestry), races, sexes, age, pre-existing comorbidities, smoking, and genetics. The …