TFOS DEWS II tear film report

MDP Willcox, P Argüeso, GA Georgiev, JM Holopainen… - The ocular …, 2017 - Elsevier
The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye
disease (DED). The Subcommittee reviewed biophysical and biochemical aspects of tears …

Evaluation of dry eye

S McGinnigle, SA Naroo, F Eperjesi - Survey of ophthalmology, 2012 - Elsevier
Dry eye is a common yet complex condition. Intrinsic and extrinsic factors can cause
dysfunction of the lids, lacrimal glands, meibomian glands, ocular surface cells, or neural …

Clinical utility of objective tests for dry eye disease: variability over time and implications for clinical trials and disease management

BD Sullivan, LA Crews, B Sönmez, MF de la Paz… - Cornea, 2012 - journals.lww.com
Purpose: To evaluate the efficacy of commonly used biomarkers in dry eye disease
management in a longitudinal observational case series study followed by an interventional …

Post-LASIK dry eye

RM Shtein - Expert review of ophthalmology, 2011 - Taylor & Francis
Laser-assisted in situ keratomileusis (LASIK) is a frequently performed corneal refractive
surgery with excellent refractive outcomes. The most common complication of LASIK is dry …

[HTML][HTML] Correlations between tear cytokines, chemokines, and soluble receptors and clinical severity of dry eye disease

KS Na, JW Mok, JY Kim, CR Rho… - … ophthalmology & visual …, 2012 - iovs.arvojournals.org
Purpose.: To determine cytokine and chemokine concentrations in the tears of patients with
dry eye disease (DED) and analyze the possible relationships with the clinical severity of …

[HTML][HTML] Dry eye disease: A review of diagnostic approaches and treatments

H Lin, SC Yiu - Saudi Journal of Ophthalmology, 2014 - Elsevier
Dry eye (DE) is a common ocular disease that results in eye discomfort, visual disturbance
and substantially affects the quality of life. It has a multifactorial etiology involving tear film …

[HTML][HTML] Vision through healthy aging eyes

N Erdinest, N London, I Lavy, Y Morad, N Levinger - Vision, 2021 - mdpi.com
As life expectancy grows, so too will the number of people adversely affected by age.
Although it is acknowledged that many conditions and diseases are associated with age …

[HTML][HTML] The ocular surface and diabetes, the other 21st Century epidemic

Y Bu, KC Shih, L Tong - Experimental Eye Research, 2022 - Elsevier
Diabetes Mellitus (DM) is a chronic metabolic disorder characterized by sustained
hyperglycemia, potentially leading to life-threatening health problems. While the …

TFOS DEWS II clinical trial design report

GD Novack, P Asbell, S Barabino, MVW Bergamini… - The ocular …, 2017 - Elsevier
The development of novel therapies for Dry Eye Disease (DED) is formidable, and relatively
few treatments evaluated have been approved for marketing. In this report, the …

[HTML][HTML] The growing need for validated biomarkers and endpoints for dry eye clinical research

NS Roy, Y Wei, E Kuklinski… - … ophthalmology & visual …, 2017 - iovs.arvojournals.org
Purpose: Biomarkers with minimally invasive and reproducible objective metrics provide the
key to future paradigm shifts in understanding of the underlying causes of dry eye disease …