Exosomes, as nanoscale extracellular vesicles (EVs), are secreted by all types of cells to
facilitate intercellular communication in living organisms. After being taken up by …

Extracellular vesicles (EVs) are microparticles released from cells in both physiological and
pathological conditions and could be used to monitor the progression of various …

Protein tyrosine phosphatase 1B (PTP1B) as a regulatory enzyme is an important target for
the early diagnosis and drug discovery of diabetes, obesity, and cancer. Herein, a …

The CRISPR/Cas12a system is accelerated by glutathione-mediated reduction of MnO2
nanosheets. By monitoring the trans-cleavage of the DNA probe, an electrochemical method …

Label-free photoelectrochemical sensors have the advantages of high sensitivity and a
simple electrode structure. However, its performance is greatly limited due to the photoactive …

Herein, single-atom iron doped carbon dots (SA Fe-CDs) were successfully prepared as
novel electrochemiluminescence (ECL) emitters with high ECL efficiency, and a biosensor …

Quantitative detection of the cancer-associated biomarker miRNA-21 is essential for the
prevention and treatment of early-stage cancer patients. In the early diagnosis of cancer …

We propose a simple and robust biosensing platform which can be used for accurate
determination of multiplex microRNA targets in biological samples. We develop the sensor …

Lung cancer is a major malignant cancer with low survival rates, and early diagnosis is
crucial for effective treatment. Herein, a biosensing platform that is self-powered derived …

The rational design of DNA tracks is an effective pathway to guide the autonomous
movement and high-efficiency recognition in DNA walkers, showing outstanding advantages …