Enrichment driven glycoproteomics: New materials, new methods, and beyond

Y Xiong, M Li, Y Liu, X Liang, G Qing - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Glycoproteomics is a rapidly growing field that aims to identify and characterize protein
glycosylation events at a system level. However, the analysis of protein glycosylation in …

Advancing mass spectrometry–based glycoproteomic software tools for comprehensive site-specific glycoproteome analysis

W Cao - Current Opinion in Chemical Biology, 2024 - Elsevier
Glycoproteome analysis at a site-specific level and proteome scale stands out as a highly
promising approach for gaining insights into the intricate roles of glycans in biological …

Prediction of glycopeptide fragment mass spectra by deep learning

Y Yang, Q Fang - Nature Communications, 2024 - nature.com
Deep learning has achieved a notable success in mass spectrometry-based proteomics and
is now emerging in glycoproteomics. While various deep learning models can predict …

Impact of glycosylation on viral vaccines

A Lembo, A Molinaro, C De Castro, F Berti… - Carbohydrate …, 2024 - Elsevier
Glycosylation is the most prominent modification important for vaccines and its specific
pattern depends on several factors that need to be considered when developing a new …

Deep Learning Prediction of Glycopeptide Tandem Mass Spectra Powers Glycoproteomics

Y Zong, Y Wang, X Qiu, X Huang, L Qiao - bioRxiv, 2024 - biorxiv.org
Protein glycosylation plays a significant role in numerous physiological and pathological
cellular functions. Glycoproteomics based on liquid chromatography-tandem mass …

Immunoglobulin A Carries Sulfated N-glycans Primarily at the Tailpiece Site—An Oxonium-Ion-Guided Approach for Site-Specific N-glycan Identification

FJ Zuniga-Banuelos, G Lemke, M Hoffmann, U Reichl… - bioRxiv, 2024 - biorxiv.org
Sulfated N-glycans from human immunoglobulin A (IgA) were recently discovered via
glycomic approaches. However, their site-specific description is still pending. Certain N …

Spectrum and Retention Time Prediction for N-Glycopeptides Using Deep Learning

S Zhang - 2023 - uwspace.uwaterloo.ca
Sequencing proteins and glycans have important clinical applications, as glycosylation is
shown to play a significant role in cellular communication and immune response. Certain …